Cygnus XL Spacecraft Departing Station Soon Live on NASA+

Cygnus XL Spacecraft Departing Station Soon Live on NASA+

Northrop Grumman's Cygnus XL cargo craft, carrying over 11,000 pounds of new science and supplies for the Expedition 73 crew, is pictured in the grips of the International Space Station's Canadarm2 robotic arm following its capture. Both spacecraft were orbiting 257 miles above Tanzania. Cygnus XL is Northrop Grumman's expanded version of its previous Cygnus cargo craft increasing its payload capacity and pressurized cargo volume.
Northrop Grumman’s Cygnus XL cargo craft is pictured in the grips of the Canadarm2 robotic arm following its capture on Sept. 18, 2025. Cygnus XL is Northrop Grumman’s expanded version of its previous Cygnus cargo craft increasing its payload capacity and pressurized cargo volume.
NASA

Live coverage of the departure of Northrop Grumman’s Cygnus XL cargo spacecraft from the International Space Station is underway on NASA+Amazon Prime, and the agency’s YouTube channel. The spacecraft’s release is scheduled for 7:05 a.m. EDT.  

Flight controllers on the ground will send commands for the space station’s Canadarm2 robotic arm to detach the Cygnus XL spacecraft from the Unity module’s Earth-facing port and maneuver it into position for release. ESA (European Space Agency) astronaut Sophie Adenot will monitor Cygnus’ systems as it departs.  

Cygnus XL will be commanded to deorbit on Saturday, March 14, to  dispose of several thousand pounds of trash during its re-entry into Earth’s atmosphere, where it will harmlessly burn up.  

The Northrop Grumman spacecraft launched in September 2025 on a SpaceX Falcon 9   rocket from Space Launch Complex 40 at Cape Canaveral Space Force Station in Florida. This mission was the first flight of the larger, more cargo-capable version of the solar-powered spacecraft.  

Northrop Grumman named the spacecraft the S.S. William “Willie” McCool in honor of the NASA astronaut who perished in 2003 during the space shuttle Columbia accident.  

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Cardiac Research and Spacewalk Preps Before Cygnus XL Spacecraft Departs

Cardiac Research and Spacewalk Preps Before Cygnus XL Spacecraft Departs

NASA astronaut and Expedition 74 flight engineer Jessica Meir works inside the International Space Station's Quest airlock, installing leg and arm components on a spacesuit and swapping components from one suit to another.
NASA astronaut Jessica Meir works inside the International Space Station’s Quest airlock, installing leg and arm components on a spacesuit and swapping components from one suit to another to prepare for a spacewalk.
NASA/Jack Hathaway

The Expedition 74 crew members spent Wednesday studying the cardiovascular system while preparing for a spacewalk to upgrade the orbital outpost’s power generation system. A U.S. cargo spacecraft is also packed and ready for its departure from the International Space Station on Thursday.

NASA flight engineers Jessica Meir and Jack Hathaway kicked off their shift with vein scans inside the Columbus laboratory module. Meir led the Venous Flow biomedical study operating the new Ultrasound 3 device and scanning Hathaway’s veins while he wore electrodes on his chest measuring his heart activity. Doctors are investigating space-caused blood flow changes that may lead to an increased risk of blood clots in astronauts.

Meir also partnered with flight engineer Sophie Adenot of ESA (European Space Agency) and filled out a questionnaire to document their sleep patterns then collected their saliva samples for preservation in a science freezer and later analysis. Meir later took a cognition test to understand how living in weightlessness affects a crew member’s spatial orientation, visual tracking, decision making, and more for the Standard Measures study.

Adenot and Meir worked together throughout Wednesday readying the Cygnus XL cargo spacecraft for its detachment from the Unity module and release into Earth orbit at 7:05 a.m. on Thursday with the Canadarm2 robotic arm. Adenot configured hardware that will enable Cygnus XL to be disconnected from Unity then closed the spacecraft’s hatch. Meir set up the equipment that will depressurize Cygnus XL in advance of its departure. NASA’s live coverage of undocking and departure begins at 6:45 a.m. on NASA+Amazon Prime, and the agency’s YouTube channel. Learn how to watch NASA content through a variety of online platforms, including social media.

Meir’s main task, however, was working with NASA flight engineer Chris Williams in the Quest airlock to configure the tools they will use on an upcoming spacewalk to ready the orbital outpost for a new roll-out solar array. Meir and Williams will work in the vacuum of space to install a modification kit and route cables on the port side of the orbital outpost. The external maintenance work will enable the next roll-out solar array to be installed on a later spacewalk after it is delivered on a SpaceX Dragon spacecraft. Williams and Hathaway then joined flight engineer Sophie Adenot of ESA (European Space Agency) and trained on a computer for the Canadarm2 robotic arm maneuvers necessary to support the spacewalkers.

The Roscosmos cosmonauts also worked on their portion of cardiac research adding to the biomedical data scientists from around the world collect and use to understand how living in space affects vascular health. Commander Sergey Kud-Sverchkov and flight engineer Sergei Mikaev once again took turns wearing sensors on their forehead, fingers, and toes that sent their blood flow data by Bluetooth adaptor to a laptop computer for analysis. Flight engineer Andrey Fedyaev began a 24-hour health monitoring session wearing electrodes and cuffs that recorded his heart’s electrical activity and blood pressure.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

More Spacewalk Preps, Advanced Research as Cargo Craft Readies for Departure

More Spacewalk Preps, Advanced Research as Cargo Craft Readies for Departure

Northrop Grumman's Cygnus XL cargo craft is pictured installed to the Unity module's Earth-facing port as the International Space Station orbited 262 miles above the Atlantic Ocean off the coast of South Africa.
Northrop Grumman’s Cygnus XL cargo craft is pictured installed to the Unity module’s Earth-facing port as the International Space Station orbited 262 miles above the Atlantic Ocean off the coast of South Africa.
NASA

The Expedition 74 crew continued its spacewalk preparations on Tuesday while keeping up vascular health research and artificial intelligence studies. Mission managers have also given the go for the departure of a U.S. cargo spacecraft from the International Space Station this week.

NASA flight engineer Jessica Meir tried on her spacesuit today with assistance from fellow NASA flight engineer Jack Hathaway inside the Quest airlock. The duo confirmed that the spacesuit is airtight and properly configured and assessed its comfort and mobility. Afterward, flight engineers Chris Williams of NASA and Sophie Adenot of ESA (European Space Agency) joined the pair and called down to mission controllers for a spacewalk procedures review. Earlier, Williams prepared a helmet for installation on a spacesuit while Adenot trained to use the Canadarm2 robotic arm to support the spacewalkers.

Meir and Williams are preparing for an upcoming spacewalk to ready the orbital outpost for a new roll-out solar array. The duo will spend about six-and-a-half-hours in the vacuum of space installing a modification kit and routing cables on the port side of the orbital outpost for the future roll-out solar array. The station’s seventh roll-out solar array will be installed on a later spacewalk to augment the main solar arrays’ power generation capabilities.

Cosmonauts Sergey Kud-Sverchkov and Sergei Mikaev joined each other again on Tuesday and applied sensors to their forehead, fingers, and toes that sent their blood flow data by Bluetooth adaptor to a laptop computer where it was recorded for analysis. Doctors will use the biomedical data to understand how living in space affects vascular health.

Kud-Sverchkov also cleaned and inspected the Zvezda service module’s ventilation system. Mikaev took turns with Roscosmos flight engineer Andrey Fedyaev continuing to test artificial intelligence tools as a way to improve crew operations and communications with mission controllers. Fedyaev earlier spent time inside the Nauka science module replacing orbital plumbing components, inspecting its ventilation system, and measuring the airflow.

Mission managers have approved the departure of Northrop Grumman’s Cygnus XL spacecraft for 7:05 a.m. EDT on Thursday after nearly six months attached to the Unity module. Robotics controllers will remotely command the Canadarm2 to uninstall Cygnus from Unity then release it into Earth orbit for a fiery, but safe reentry above the South Pacific Ocean two days later.

NASA’s live coverage of undocking and departure begins at 6:45 a.m. on NASA+Amazon Prime, and the agency’s YouTube channel. Learn how to watch NASA content through a variety of online platforms, including social media.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

More Spacewalk Preps, Advanced Research as Cargo Craft Readies for Departure

More Spacewalk Preps, Advanced Research as Cargo Craft Readies for Departure

Northrop Grumman's Cygnus XL cargo craft is pictured installed to the Unity module's Earth-facing port as the International Space Station orbited 262 miles above the Atlantic Ocean off the coast of South Africa.
Northrop Grumman’s Cygnus XL cargo craft is pictured installed to the Unity module’s Earth-facing port as the International Space Station orbited 262 miles above the Atlantic Ocean off the coast of South Africa.
NASA

The Expedition 74 crew continued its spacewalk preparations on Tuesday while keeping up vascular health research and artificial intelligence studies. Mission managers have also given the go for the departure of a U.S. cargo spacecraft from the International Space Station this week.

NASA flight engineer Jessica Meir tried on her spacesuit today with assistance from fellow NASA flight engineer Jack Hathaway inside the Quest airlock. The duo confirmed that the spacesuit is airtight and properly configured and assessed its comfort and mobility. Afterward, flight engineers Chris Williams of NASA and Sophie Adenot of ESA (European Space Agency) joined the pair and called down to mission controllers for a spacewalk procedures review. Earlier, Williams prepared a helmet for installation on a spacesuit while Adenot trained to use the Canadarm2 robotic arm to support the spacewalkers.

Meir and Williams are preparing for an upcoming spacewalk to ready the orbital outpost for a new roll-out solar array. The duo will spend about six-and-a-half-hours in the vacuum of space installing a modification kit and routing cables on the port side of the orbital outpost for the future roll-out solar array. The station’s seventh roll-out solar array will be installed on a later spacewalk to augment the main solar arrays’ power generation capabilities.

Cosmonauts Sergey Kud-Sverchkov and Sergei Mikaev joined each other again on Tuesday and applied sensors to their forehead, fingers, and toes that sent their blood flow data by Bluetooth adaptor to a laptop computer where it was recorded for analysis. Doctors will use the biomedical data to understand how living in space affects vascular health.

Kud-Sverchkov also cleaned and inspected the Zvezda service module’s ventilation system. Mikaev took turns with Roscosmos flight engineer Andrey Fedyaev continuing to test artificial intelligence tools as a way to improve crew operations and communications with mission controllers. Fedyaev earlier spent time inside the Nauka science module replacing orbital plumbing components, inspecting its ventilation system, and measuring the airflow.

Mission managers have approved the departure of Northrop Grumman’s Cygnus XL spacecraft for 7:05 a.m. EDT on Thursday after nearly six months attached to the Unity module. Robotics controllers will remotely command the Canadarm2 to uninstall Cygnus from Unity then release it into Earth orbit for a fiery, but safe reentry above the South Pacific Ocean two days later.

NASA’s live coverage of undocking and departure begins at 6:45 a.m. on NASA+Amazon Prime, and the agency’s YouTube channel. Learn how to watch NASA content through a variety of online platforms, including social media.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Spacewalk Preps and Health Checks Using Augmented Reality, Artificial Intelligence

Spacewalk Preps and Health Checks Using Augmented Reality, Artificial Intelligence

NASA astronaut and Expedition 74 flight engineer Jack Hathaway smiles for a portrait inside the International Space Station’s cupola while photographing a sample chamber for the Rhodium Biomanufacturing 03 biotechnology experiment. The investigation uses living systems such as microorganisms and cell cultures to produce materials and biomolecules on a commercial scale. Results may support the production of food, pharmaceuticals, and other materials during long‑duration spaceflight.
NASA astronaut Jack Hathaway smiles for a portrait inside the International Space Station’s cupola while photographing scientific hardware for a biomanufacturing experiment.
NASA/Jack Hathaway

Spacewalk preparations are underway aboard the International Space Station as two astronauts check their spacesuits and review procedures. The Expedition 74 crew also experimented with augmented reality and artificial intelligence to conduct health checks in space. Meanwhile, a U.S. cargo spacecraft nears it departure this week.

NASA flight engineers Jessica Meir and Chris Williams joined each other on Monday working on a pair of spacesuits and reviewing procedures for a spacewalk targeted for March 18. The duo partnered up in the Quest airlock and cleaned the suit cooling loops that regulate an astronaut’s temperature during a spacewalk. Meir and Williams also refilled suit components with water, inspected a suit helmet, and prepared Quest for the upcoming spacewalk operations.

The astronauts also reviewed the procedures they will use after they exit Quest in their spacesuits for a six-and-a-half-hour spacewalk. Meir and Williams will install a modification kit and route cables on the port side of the orbital outpost for a future roll-out solar array. The seventh roll-out solar array will be installed on a later spacewalk to augment the main solar arrays’ power generation capabilities.

Flight engineers Jack Hathaway of NASA and Sophie Adenot of ESA (European Space Agency) took turns performing augmented‑reality‑guided ultrasound scans using the EchoFinder-2 biomedical device inside the Columbus laboratory module. After each crew member scanned the other’s abdomen and vascular system, artificial intelligence analyzed the ultrasound image and confirmed organ identification. The objective of the human research study is to reduce reliance on ground support for medical procedures as a space crew flies farther away from Earth.

Roscosmos cosmonauts Sergey Kud-Sverchkov and Sergei Mikaev teamed up on a pair of biology experiments Monday both observing the human circulatory system in weightlessness. First, the station commander and flight engineer measured their blood pressure and more while wearing arm, wrist, and finger cuffs. Afterward, the duo applied sensors to their forehead, fingers, and toes that sent their blood flow data by Bluetooth adaptor to a laptop computer where it was recorded for analysis. Doctors will use the biomedical data to understand how living in space affects vascular health.

Flight engineer Andrey Fedyaev primarily spent his day on life support maintenance throughout the orbital outpost’s Roscosmos segment. During the first half of his shift, Fedyaev serviced the Elektron oxygen generator purging the device of nitrogen and repressurizing its components inside the Zvezda service module. After lunchtime, he filtered and transferred water between tanks to ensure the station’s drinking‑water supply chain remains clean and uncontaminated.

Northrop Grumman’s Cygnus XL cargo spacecraft is due to depart the station Thursday, March 12, ending a near six-month stay that began on Sept. 18, 2025. The astronauts will finalize packing Cygnus with trash and disposable cargo midweek then configure the spacecraft for its robotic removal from the Unity module. Afterward, robotics controllers will remotely command the Canadarm2 robotic arm to uninstall Cygnus from Unity then release it into Earth orbit for a fiery, but safe reentry above the South Pacific Ocean.

Watch NASA’s live coverage of undocking and departure beginning at 6:45 a.m. EDT on NASA+Amazon Prime, and the agency’s YouTube channel. Learn how to watch NASA content through a variety of online platforms, including social media.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia