New File Download Process for PSI Large Requests

A recent update to the PSI database improves how large dataset downloads are handled, resulting in more efficient processing for users.

Download requests larger than 1GB are now delivered via email, rather than downloading directly from the website. This allows the system to prepare your files in the background so you can continue working without delays, accessing the files at your convenience once your request is processed.

Why The Change?

This update improves user experience by:

• Reducing system lag and download interruptions.
• Allowing you to stay productive while files are processed in the background.
• Increasing reliability of large downloads.
• Delivering files in manageable parts, making them easier to handle and extract.

How Does it Work?

To download files larger than 1GB:

1. Users select 2 or more desired files and click “Download Zip.”

2. In the Prepared Large Download section:

• Enter the email address where the download access links should be sent.

• Check the box to confirm: “I understand large downloads are delivered in multiple parts via email.”

• Click “Send me the links.”

3. Users will receive an email confirming the download request has been submitted.

4. Once the files are ready, users receive a second email with link(s) to access the download. NOTE: Download links are valid for 7 days from the time you receive the email. Be sure to save the requested files before the links expire.

Best Practices

To ensure a smooth and efficient download experience, especially when working with large datasets, follow these best practices to help reduce processing time, prevent errors, and simplify file handling.

• Download only what you need: Smaller requests are processed faster.
• Split very large requests: If possible, divide and submit large requests into smaller sets to speed up processing.
• Avoid simultaneous large requests: Submit one large download at a time for smoother performance.
• Before extracting, save all ZIP parts to the same folder: This ensures proper extraction of multi-part downloads.
• Download promptly: Remember, download links will expire. Save your files while the link is active.
• Use a reliable email address: Double-check for typos and check your spam/junk folder if you don’t receive the emails.

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Joe A. Adam Presents Ring Sheared Drop (RSD) Research at 2025 ISSRDC

At the virtual 2025 ISS Research and Development Conference (ISSDRC), Joe A. Adam of Rensselaer Polytechnic Institute, presented the topic titled “Surface Science in Microgravity – Fluid Geometry in the Ring-Sheared Drop,” presented to a broad audience from academia and the scientific community during the Physical Sciences and Materials Development session.

Dr. Adam provided a comprehensive overview of the Ring Sheared Drop (RSD) hardware, experiment campaigns and the evolving role of RSD in advancing biophysical science, particularly in the characterization of proteins. Leveraging the absence of gravity aboard the ISS, the RSD enables researchers to isolate shear-induced aggregation processes relevant to neurodegenerative diseases such as Alzheimer’s and Parkinson’s, offering insight into mechanisms that are difficult to observe with ground-based experiments.

The presentation traced the RSD development, beginning with the initial campaign in 2016 which was funded by Biological and Physical Sciences (BPS) for hardware development and the first science campaign, and culminating in the most recent 2025 flight campaign, which involved the study of three key proteins: Immunoglobulin G (IgG), Insulin, and Human Serum Albumin (HSA).

A highlight of the session was a discussion of the RSD’s custom camera configuration, which has enabled a novel fluid characterization technique known as Particle Tracking Velocimetry (PTV). This method allows researchers to visually track particle motion within the fluid drop, supporting the validation and refinement of theoretical and computational models describing protein behavior in microgravity.

Adam further explained how in-situ imaging and velocimetry techniques, enabled by the unique RSD camera setup, enhance the analysis of fluid flow and shear-driven aggregation at the molecular level.

The presentation showcased a series of comparative videos from past and current RSD campaigns, illustrating protein dynamics under varying sample compositions. He emphasized how flight data are being compared against Earth analog experiments to 1) validate predictive models and 2) inform the design of future microgravity research – the two-fold focus of the research from the beginning.

The session concluded with a summary of preliminary findings from the 2025 campaign, including multi-geometry rheometry results, which offer deeper insight into the viscoelastic behavior of proteins under shear. These findings may well contribute to the development of future pharmaceutical and therapeutic strategies.

To view the entire presentation, a recording is available for downloaded from the 2025 ISSRDC site.

Visit the Physical Sciences Informatics (PSI) database to access experiment data from two RSD campaigns, Interfacial Bioprocessing of Pharmaceuticals (IBP-I) and Amyloid Fibril Formation (AFF) with additional RSD data planned for release in 2026.

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Astronaut Candidates Get to Work at Johnson Space Center

NASA announced its newest class of astronaut candidates on Sept. 22, 2025, at the agency’s Johnson Space Center in Houston. After the welcome ceremony, the 10 highly qualified individuals rolled up their sleeves and prepared for the next step in their journey to the stars: nearly two years of training to become flight-eligible for missions to low Earth orbit, the Moon, and ultimately, Mars.

The training astronaut candidates complete is comprehensive and rigorous. They learn about NASA’s history and vision, and how astronauts advance the agency’s mission. They take classes on space health – gaining an understanding of radiation exposure, microgravity’s effects on the human body, space food and nutrition, and how to use the exercise equipment aboard the International Space Station. They also study first aid and practice providing medical care for crewmates. Each candidate will receive flight training, learning to pilot or improving their current piloting skills through the T-38 supersonic jet and other aviation platforms.

With NASA’s plans for the future of exploration, this class of astronauts may have opportunities to fly to low Earth orbit, or even beyond. Some may contribute to research and technology investigations taking place aboard the space station – which is about to celebrate 25 years of continuous human presence in space. Others may venture to the Moon to prepare for future Mars missions.   

To be ready for any destination, this class will complete both space station training and advanced preparation for deep space. These exercises allow astronaut candidates to work through problems and build relationships with their classmates while preparing them for space flights.

“Training was such an intense period that we got to know each other really well,” said NASA astronaut Anil Menon, who joined the agency as part of the 2021 class – astronaut group 23. “Now when we come together, there are these moments – like we might be handing off a capcom shift, or we might be flying a jet together – and in those moments, I feel like I know them so well that we know how to navigate all sorts of challenges together and just be our best selves as a team.”

Astronaut candidate training also teaches foundational skills that can be applied to any destination in space. The group will complete several dives in the Neutral Buoyancy Laboratory, simulating spacewalks in different environments and learning how to do maintenance tasks in microgravity with a full-scale underwater mockup of the International Space Station as their worksite. They will also train inside other mockups of space vehicles, learning emergency procedures, maintenance, and repair of spacecraft, along with how to contribute to future developmental programs.

Robotics training will prepare them to use the station’s Canadarm2 robotic arm. They will trek through the wilderness as part of their land and water survival training, and they will study geology in the classroom and in the field. The group will practice tasks in a variety of simulations, leveraging Johnson’s world-class facilities, virtual reality, and immersive technologies. Additionally, the class will work shifts in the Mission Control Center in Houston to experience a day in the life of the people who keep watch over the astronauts and vehicles.

Astronaut candidates who successfully complete the training program celebrate their achievement in a graduation ceremony, after which they are officially flight-eligible members of NASA’s astronaut corps. They will also receive office and ground support roles at Johnson while they await future flight assignments.

“I’ve been exposed to a lot of different parts of what we do at Johnson Space Center, working both with the current increment of supporting operations aboard the International Space Station, as well as supporting some development of the Orion spacecraft and Artemis II preparations,” said NASA astronaut Chris Birch, another member of astronaut group 23.

Many members of NASA’s active astronaut corps emphasize that the learning does not stop when astronaut candidate training ends. “You have the foundational training and you continue to build off of that,” said Deniz Burnham, adding that the hardest days can be the most educational. “You get to learn, you get to improve, and then you’re still getting the opportunity. It’s such a positively unique experience and environment, and you can’t help but be grateful.”

As NASA astronaut Frank Rubio, class mentor, told the group, “You’ll become part of a legacy of those who trained before you, continuing the adventure they started, and looking ahead to future human exploration.”

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Linda E. Grimm

NASA’s Webb Telescope Studies Moon-Forming Disk Around Massive Planet

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NASA’s Webb Telescope Studies Moon-Forming Disk Around Massive Planet

NASA’s James Webb Space Telescope has provided the first direct measurements of the chemical and physical properties of a potential moon-forming disk encircling a large exoplanet. The carbon-rich disk surrounding the world called CT Cha b, which is located 625 light-years away from Earth, is a possible construction yard for moons, although no moons are detected in the Webb data.

The results published today in The Astrophysical Journal Letters.

The young star the planet orbits is only 2 million years old and still accreting circumstellar material. However, the circumplanetary disk discovered by Webb is not part of the larger accretion disk around the central star. The two objects are 46 billion miles apart.

Observing planet and moon formation is fundamental to understanding the evolution of planetary systems across our galaxy. Moons likely outnumber planets, and some might be habitats for life as we know it. But we are only now entering an era where we can witness their formation.

This discovery fosters a better understanding of planet and moon formation, say researchers. Webb’s data is invaluable for making comparisons to our solar system’s birth over 4 billion years ago.

“We can see evidence of the disk around the companion, and we can study the chemistry for the first time. We’re not just witnessing moon formation — we’re also witnessing this planet’s formation,” said co-lead author Sierra Grant of the Carnegie Institution for Science in Washington.

“We are seeing what material is accreting to build the planet and moons,” added main lead author Gabriele Cugno of the University of Zürich and member of the National Center of Competence in Research PlanetS.

Image A: Circumplanetary Disk (Artist’s Concept)

Dissecting starlight

Infrared observations of CT Cha b were made with Webb’s MIRI (Mid-Infrared Instrument) using its medium resolution spectrograph. An initial look into Webb’s archival data revealed signs of molecules within the circumplanetary disk, which motivated a deeper dive into the data. Because the planet’s faint signal is buried in the glare of the host star, the researchers had to disentangle the light of the star from the planet using high-contrast methods.

“We saw molecules at the location of the planet, and so we knew that there was stuff in there worth digging for and spending a year trying to tease out of the data. It really took a lot of perseverance,” said Grant.

Ultimately, the team discovered seven carbon-bearing molecules within the planet’s disk, including acetylene (C₂H₂) and benzene (C₆H₆). This carbon-rich chemistry is in stark contrast to the chemistry seen in the disk around the host star, where the researchers found water but no carbon. The difference between the two disks offers evidence for their rapid chemical evolution over only than 2 million years.

Genesis of moons

A circumplanetary disk has long been hypothesized as the birthplace of Jupiter’s four major moons. These Galilean satellites must have condensed out of such a flattened disk billions of years ago, as evident in their co-planar orbits about Jupiter. The two outermost Galilean moons, Ganymede and Callisto, are 50% water ice. But they presumably have rocky cores, perhaps either of carbon or silicon.

“We want to learn more about how our solar system formed moons. This means that we need to look at other systems that are still under construction. We’re trying to understand how it all works,” said Cugno. “How do these moons come to be? What are their ingredients? What physical processes are at play, and over what timescales? Webb allows us to witness the drama of moon formation and investigate these questions observationally for the first time.”

In the coming year, the team will use Webb to perform a comprehensive survey of similar objects, to better understand the diversity of physical and chemical properties in the disks around young planets.

The James Webb Space Telescope is the world’s premier space science observatory. Webb is solving mysteries in our solar system, looking beyond to distant worlds around other stars, and probing the mysterious structures and origins of our universe and our place in it. Webb is an international program led by NASA with its partners, ESA (European Space Agency) and CSA (Canadian Space Agency).

To learn more about Webb, visit:

https://science.nasa.gov/webb

Related Information

Read more: NASA’s Webb Finds Planet-Forming Disks Lived Longer in Early Universe

Explore more: ViewSpace Detecting Other Worlds: Direct Imaging

Explore more: How to Study Exoplanets: Webb and Challenges

Read more: Webb’s Star Formation Discoveries

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