Cancer Treatment, Cartilage Repair, and Spacesuit Checks Wrap Up Week

Cancer Treatment, Cartilage Repair, and Spacesuit Checks Wrap Up Week

NASA astronauts Jessica Meir and Jack Hathaway, both Expedition 74 flight engineers, work together to process stem cell samples aboard the International Space Station’s Kibo laboratory module. Meir nourished the stem cells inside Kibo's Life Science Glovebox after Hathaway retrieved them from a science freezer, thawed them, and handed them over for treatment. The research may lead to the development of space-designed therapies to treat cancer and blood conditions.
NASA astronauts Jessica Meir and Jack Hathaway work together to process stem cell samples aboard the Kibo laboratory module. Meir nourished the stem cells inside Kibo’s Life Science Glovebox after Hathaway retrieved them from a science freezer, thawed them, and handed them over for treatment. The research may lead to the development of space-designed therapies to treat cancer and blood conditions.
NASA

Experiments exploring cancer treatments and cartilage repair topped the Expedition 74 crew’s research schedule on Friday. Two cosmonauts are also gearing up for a spacewalk in less than a week.

Doctors are taking advantage of the International Space Station’s weightless environment to develop and test advanced cancer treatments. Two experiments taking place aboard the orbital outpost on Friday are looking at different therapies and exploring how microgravity impacts their effectiveness.

NASA flight engineer Chris Williams continued the Space Cancer Therapeutics investigation by processing samples of fruit flies engineered with a pancreatic‑cancer genetic profile and treated with an anti‑cancer drug. Williams exposed one group of flies to artificial gravity and a second group to microgravity. Both sets will be frozen for preservation and returned to Earth aboard a SpaceX Dragon cargo spacecraft. Researchers will analyze the samples to assess the therapy’s effectiveness, understand its underlying molecular mechanisms, and determine microgravity’s influence on cancer development. Fruit flies are ideal for this research because their physiology is well understood, allowing scientists to track how cancer‑related processes change in different spaceflight conditions.

NASA flight engineer Jack Hathaway worked in the Harmony module observing DNA-mimicking materials for their ability to form stable structures in microgravity and potentially fight cancer. Hathaway pointed a light-measuring device at the manufactured nanoparticles that resemble the natural building blocks of DNA to evaluate the quality of the samples. The biotechnology study is testing the tiny, engineered materials—loaded with a cancer‑fighting drug—for their ability to reach target cancer cells and prevent unwanted side effects possibly leading to the development of a new type of cancer treatment.

NASA flight engineer Jessica Meir spent her shift treating samples of cartilage cells inside the Kibo laboratory module’s Life Science Glovebox to learn how human cartilage builds and repairs itself when gravity is removed. Doctors will use the insights from the biotechnology experiment to learn how to create replacement cartilage, treat arthritis and joint damage, and understand the effects of weightlessness on an astronaut’s joint health.

Flight engineer Sophie Adenot of ESA (European Space Agency) spent her day reorganizing and transferring cargo in and out of the SpaceX Dragon cargo spacecraft docked to the Harmony module’s forward port. Adenot adjusted a variety of science freezers to access cargo pallets and other research hardware installed inside Dragon for stowage aboard the space station.

Roscosmos cosmonauts Sergey Kud-Sverchkov and Sergey Mikaev, station commander and flight engineer respectively, tested a pair of Orlan spacesuits in the Poisk module’s airlock checking the suits for pressure leaks, functionality, and mobility. Flight engineer Andrey Fedyaev assisted the duo with the suit checks then moved on and checked components that support the Elektron oxygen generator in the Roscosmos segment of the orbital outpost.

Learn more about station activities by following the space station blog, @space_stationon X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Keeping NASA Flying: Ground Crews Ensure Aircraft Readiness

Keeping NASA Flying: Ground Crews Ensure Aircraft Readiness

4 min read

Preparations for Next Moonwalk Simulations Underway (and Underwater)

The back of a white jet aircraft’s wing and tails are seen in this image. One wheel and an attached test object, shaped like a wing, hangs from the bottom of the jet. A man in a black jacket, with yellow reflective coating, stands underneath and raises one hand to the aircraft. The man is wearing ear protection. Desert sand and mountains are seen in the background.
NASA crew chief Walt Kondracki checks an F-15 aircraft Tuesday, March 17, 2026, at NASA’s Armstrong Flight Research Center in Edwards, California. Ground crews, made of various roles, maintain the aircraft to be ready for each mission.
NASA/Carla Escamilla

From high‑speed research flights to high‑altitude science campaigns, NASA depends on aircraft that perform at their best and the ground crews who keep them mission ready.

At NASA’s Armstrong Flight Research Center in Edwards, California, specially trained maintenance crews are essential to keeping the agency’s aircraft flying safely and reliably.

This year, NASA added two F-15s and a Pilatus PC-12 to its fleet at Armstrong. These aircraft – alongside platforms such as the high-altitude ER-2s and NASA’s newest X-plane, the X-59 – reflect a wide range of capabilities. The maintenance staff is responsible for keeping each one mission ready.

Three men, two wearing tan flight suits, and one wearing a black jacket with stripes of reflective yellow coating, walk to the right side of a jet aircraft. The aircraft faces forward and the canopy is open. Two wheels, intakes, wings, and tails are in view of the white aircraft. The aircraft sits on a concrete ramp with desert sand and mountains in the background.
NASA pilot Nils Larson, left, walks next to crew chief Walt Kondracki, right, by an F-15 aircraft Tuesday, Jan. 13, 2026, at NASA’s Armstrong Flight Research Center in Edwards, California. In the background, NASA mechanic Tim Logan secures the cockpit inside of the F-15, and flight test engineer A.J. Jaffe stands to the right.
NASA/Christopher LC Clark

“That’s the beauty of our Armstrong maintenance teams. They adapt to any type of change,” said Jose “Manny” Rodriguez, NASA Armstrong Gulfstream G-IV crew chief. “One day you could have an instrument being loaded, and the next day it may be aircraft reconfiguration, all while other aircraft systems may need fixing. They adapt and they overcome any situation.”

Each aircraft supports a specific mission, whether it’s conducting science research, serving as a support or chase aircraft, or assisting NASA rocket launches. The aircraft fly at different speeds, carry specialized hardware, and require maintenance crews to stay agile with fast-paced changes.

To ensure NASA can make aeronautics and science advancements safely, the crews work continuously, checking on the ejection seats, filling the tanks with fuel, and changing out brakes, wheels, wiring, and hardware constantly, all of which can degrade with each flight.

Four men surround a round object attached to an aircraft wing with shelves and wiring inside. One man’s arms are inside of the object, and he is adjusting a gold-colored piece of metal equipment. The other men watch as he works on the hardware.
From left, NASA avionics technician Jesse Orellana; quality assurance employee Jose Prieto; mechanic Francisco Rodriguez; and mechanic Vincent Moreno work on an ER-2 aircraft Monday, Jan. 26, 2026, at NASA’s Armstrong Flight Research Center in Edwards, California.
NASA/Christopher LC Clark

On any given day, an aircraft may be flight-ready for a mission, undergoing scheduled maintenance or modifications, or down for longer-term care.

There are typically multiple NASA Armstrong aircraft in the air in one day. Currently, the center’s C-20A is flying in Peru and Panama, the X-59 is often  flying twice per day with a chase plane, and the center’s ER-2 is flying in Colorado, supporting the Geological Earth Mapping Experiment (GEMx). All this work is happening at the same time, and Armstrong’s skilled maintenance staff is prepping and fixing aircraft as needed along the way.

The team includes mechanics with both military and civilian backgrounds, and the job involves a lot of on-the-job training.

Maintenance crews are composed of:

  • a crew chief – the person in charge of the airplane
  • an avionics technician, who specializes in navigation, communication, and flight control systems
  • quality assurance personnel, who oversee the work being done
  • additional mechanics assigned to each airplane

After the maintenance crew ensures the aircraft is in the best condition possible, the team tows it out to the flightline, and it becomes ready for operations. The NASA pilot assigned to the mission will walk around the aircraft with the assigned crew chief for a final safety check before flight.

“There is a crew chief assigned to every aircraft,” Rodriguez said. “The crew chief is responsible for the integrity of that aircraft, and at the end of the day, his signature and the pilot’s together are what constitutes that the aircraft is safe for flight.”

Maintenance crews track each flight to help ensure it completes the mission without returning early. If an aircraft does return to base early, the maintenance team stands ready. When it lands, the crew is right there again, helping the research team complete the mission and fixing whatever is needed to stay nimble and ready for the next flight.

“It’s difficult at times to work with different airplanes from both the civilian and military sides, but it’s very rewarding to see that we have the capability and the expertise to keep these aircraft flying,” Rodriguez said.

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Dede Dinius

NASA to Compete Contract for Jet Propulsion Laboratory Management

NASA to Compete Contract for Jet Propulsion Laboratory Management

NASA's Jet Propulsion Laboratory Campus
NASA’s Jet Propulsion Laboratory in Southern California.
Credit: NASA

NASA announced plans Friday to compete the next contract for managing and operating the agency’s federally funded research and development center (FFRDC) in Southern California at the Jet Propulsion Laboratory (JPL), to ensure continued accountability and strong value for U.S. taxpayers.

The California Institute of Technology (Caltech) has managed the laboratory since its inception in the 1930s, and previous NASA contracts for its management and operations have been awarded sole source to the university since the facility was transferred from the U.S. Army to NASA in 1958.

The rapid growth of the U.S. space economy indicates there may now be a viable competitive market for programmatic and institutional elements of the FFRDC operations.

Conducting a competition for this contract enables NASA to assess the potential benefits of alternative management approaches to the FFRDC, including opportunities to enhance mission performance, innovation, and overall cost and operational efficiency, consistent with federal competition requirements.

This decision is part of a broader governmentwide and agency effort to find efficiencies, strengthen performance, and drive mission outcomes faster and more affordably.

“The Jet Propulsion Laboratory has delivered some of the most extraordinary scientific and engineering achievements in NASA’s history,” said NASA Administrator Jared Isaacman. “As America’s space economy evolves, we have a responsibility to the American people and the scientific community to evaluate how we can execute faster, operate more efficiently, and continue to deliver world-class science and engineering at the highest level. The decision to compete this contract reflects NASA’s commitment to strong stewardship of taxpayer resources and positions Jet Propulsion Laboratory to continue driving world-changing scientific discovery and technological innovation for decades to come.”

The work conducted at JPL remains critically important to the agency, and NASA is committed to maintaining continuity for active and future missions throughout the procurement process. NASA also is committed to maintaining the FFRDC’s existing physical location.

This approach is consistent with broader government practices, including at the Department of Energy, which has held full and open competitions for five of its 16 FFRDC management and operations contracts over the past 10 years.

The current contract with Caltech began Oct. 1, 2018, and runs through Sept. 30, 2028, with a potential maximum value of $30 billion, if all options are exercised. NASA has initiated the procurement process to compete the contract. Beginning this process now allows the agency sufficient time to conduct a comprehensive competition and award cycle while maintaining continuity for ongoing missions and laboratory operations.

For information about NASA and agency programs, visit:

https://www.nasa.gov

-end-

George Alderman / Cheryl Warner
Headquarters, Washington
202-358-1600
george.a.alderman@nasa.gov / cheryl.m.warner@nasa.gov

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May 22, 2026

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Cheryl Warner

NASA Announces Realignment to Accelerate Mission Delivery

NASA Announces Realignment to Accelerate Mission Delivery

NASA meatball
Credit: NASA

Editor’s Note: This advisory was updated May 22, 2026 to include a retirement.

NASA announced Friday an agencywide realignment to increase mission focus and move out on the National Space Policy. These changes position the agency to better deliver on the nation’s highest‑priority objectives with speed and efficiency.

During the Ignition event in late March, NASA Administrator Jared Isaacman and agency leaders outlined the most pressing objectives to deliver on the next chapter of American leadership in space. President Trump’s Executive Order Ensuring American Space Superiority, otherwise known as the National Space Policy, directed NASA to focus talent and resources on objectives including accelerating the Artemis program, establishing a Moon Base, developing a nuclear space reactor, igniting the orbital economy, and expanding missions of science and discovery.

To support the agency’s ambitious short- and long-term goals, NASA is taking action to increase specialization at centers and integrate mission directorates, elevating delivery of technically excellent work. Some of these actions include:

  • Center directors will continue reporting to Associate Administrator Amit Kshatriya, empowered to foster the unique capabilities of each center, and strengthen investments in infrastructure and the health of their workforce.
  • Mission directorates will now report directly to the administrator, ensuring focus on the mission and enabling them to leverage resources across centers, industry, and international partnerships with greater speed and efficiency.
  • The associate administrator also now serves as NASA chief engineer, reinforcing the agency’s technical backbone and ensuring continuity and autonomy in critical engineering decisions.
  • The agency continues to focus on rebuilding core competencies, insourcing contractors to civil servants where appropriate, strengthening the intern pipeline, and leveraging the agency’s joint recruitment initiative with the U.S. Office of Personnel Management, NASA Force, to build a strong, sustainable workforce for generations to come.

“This initiative reflects NASA’s extreme focus on executing the mission in direct support of the National Space Policy. We are focusing resources on the most pressing objectives only NASA is capable of undertaking and liberating the workforce from unnecessary bureaucracy and obstacles that impede progress. We aim to rebuild competencies and instill a culture that attracts the best and brightest capable of pursuing the most demanding engineering challenges and moving safely and urgently,” said Isaacman. “There will be no reduction in force, no program cancellations, no closures, but we will achieve cost savings through more efficient execution and taking an active role in delivering the outcomes the world has been waiting for from NASA. This is how we deliver on the mission, meet the moment, and continue to make history on behalf of the American people.”

Mission directorate realignment is as follows:

  • Human Spaceflight Mission Directorate (HSMD): With human spaceflight operational to both low Earth orbit and the Moon, the Exploration Systems Development Mission Directorate and Space Operations Mission Directorate will unify as HSMD.
  • Research and Technology Mission Directorate (RTMD): NASA will integrate the Aeronautics Research Mission Directorate and Space Technology Mission Directorate into the new RTMD. As a combined research, space technology, and aeronautics organization charged with nuclear power and propulsion development, RTMD will ensure NASA has the capabilities needed for the mission of today and the future.
  • Science Mission Directorate (SMD): Remains unchanged and continues to provide the foundation for NASA’s world‑leading scientific discovery.

Additional leadership roles, in alphabetical order, include:

  • John Bailey, associate administrator, Mission Support Directorate
  • Kevin Coggins, director, SCaN (Space Communications and Navigation), RTMD
  • Wesley Deadrick, director, Katherine Johnson IV&V Facility
  • Jamie Dunn, director, NASA’s Goddard Space Flight Center
  • Carlos García-Galán, program manager, Moon Base, HSMD
  • Dr. Lori Glaze, associate administrator, HSMD
  • Laurie Grindle, director, Aeronautics Division, RTMD
  • Marvin Horne, deputy assistant administrator for Procurement
  • Brian Hughes, director, NASA’s Kennedy Space Center
  • Kathleen Karika, associate administrator, Office of International and Interagency Relations, OIIR
  • Dr. James Kenyon, associate administrator, RTMD
  • Kelvin Manning, deputy associate administrator, HSMD
  • Meredith McKay, deputy associate administrator, OIIR
  • Dave Mitchell, special assignment lead for NASA Headquarters Relocation
  • Joel Montalbano, deputy associate administrator, HSMD
  • Bradley Niese, associate administrator for Procurement
  • Eli Ouder, acting deputy associate administrator, Mission Support Directorate
  • Jeremy Parsons, program manager, Artemis, HSMD
  • Bob Pearce to retire as head of ARMD after an amazing 36-year career at NASA
  • Wanda Peters, deputy associate administrator, RTMD
  • Dawn Schaible, director, NASA’s Glenn Research Center
  • Cynthia Simmons, deputy director, NASA’s Goddard Space Flight Center
  • Steve Sinacore, acting director, Space Reactor Office; program manager for SR-1, LR-1, RTMD
  • Adam Steltzner, chief engineer for Special Projects
  • Greg Stover, director, Advanced Research and Technology Division, RTMD
  • Dana Weigel, program manager, Low Earth Orbit, HSMD

Leadership at unlisted centers remains unchanged.

For more, please visit:

https://www.nasa.gov/nasa-leadership

-end-

Bethany Stevens / Camille Gallo
Headquarters, Washington
202-358-1600
bethany.c.stevens@nasa.gov / camille.m.gallo@nasa.gov

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Cheryl Warner