OSDR Chats with Begum Mathyk

OSDR Chats with Begum Mathyk

OSDR Chats: Dr Begum Mathyk Presents Latest Research in this OSDR-Enabled Publication

Welcome to “OSDR Chats,” an interview series featuring authors of publications that were enabled by the Open Science Data Repository (OSDR). Researchers share highlights and insights into their work, emphasizing the valuable roles played by the OSDR in their research. This newest interview features Dr Begum Mathyk  who discusses her paper “Spaceflight induces changes in gene expression profiles linked to insulin and estrogen“, one of 45 that were part of the Nature Press package publications.

Organismal adaptations to spaceflight have been characterized at the molecular level in model organisms, including Drosophila and C. elegans. This study extends such molecular work to energy metabolism and sex hormone signaling in mice and humans. The findings of this research underscore the critical importance of in-depth hormonal studies on the effects of space travel, which are vital for enabling further human exploration of space. The study also emphasizes the need for further research focused on women’s health and the development of tailored healthcare strategies for space environments.

OSDR recently spoke to Dr Mathyk to hear about the highlights of this publication and about how the OSDR and Analysis Working Groups (AWGs) enabled this publication.

Link to Publication; Link to Datasets: OSD-48, OSD-98, OSD-99, OSD-100, OSD-101, OSD-102, OSD-103, OSD-104, OSD-105, OSD-168, OSD-238, OSD-239, OSD-240, OSD-241, OSD-254, OSD-530; Learn more about Analysis Working Groups (AWGs); Request to Join Analysis Working Groups (AWGs)

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NASA’s SpaceX Crew-11 Rocket Arrives at Launch Pad

NASA’s SpaceX Crew-11 Rocket Arrives at Launch Pad

SpaceX rocket rolling to the launch pad on a transport truck.
A SpaceX Dragon spacecraft atop the company’s Falcon 9 rocket rolls to the launch pad at Launch Complex 39A at NASA’s Kennedy Space Center in Florida on Sunday, July 27, 2025, for NASA’s SpaceX Crew-11 mission.

The SpaceX Falcon 9 rocket, with the Dragon crew spacecraft atop, for NASA’s SpaceX Crew-11 mission rolled out to the launch pad early Sunday, July 27, at the agency’s Kennedy Space Center in Florida. The rocket was raised to vertical position at Kennedy’s Launch Complex 39A, awaiting lift off no earlier than 12:09 p.m. EDT on Thursday, July 31.

The Crew-11 mission will carry NASA astronauts Zena Cardman and Mike Fincke, JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, and Roscosmos cosmonaut Oleg Platonov to the International Space Station for a long-duration mission. Crew-11 will conduct new and exciting scientific research aboard the orbiting laboratory to prepare for human exploration beyond low Earth orbit and benefit life on Earth. This is first spaceflight for Cardman and Platonov, the second for Yui, and the fourth for Fincke.

The flight is the 11th crew rotation mission with SpaceX to station, and the 12th human spaceflight under NASA’s Commercial Crew Program. The Crew-11 cadre will fly aboard the SpaceX Dragon crew spacecraft that previously flew NASA’s SpaceX Demo Mission-2, Crew-2, Crew-6, and Crew-8, in addition to Axiom Mission 1, the first private astronaut mission to the microgravity laboratory.

Keep up with the Crew-11 mission by following along on the mission blog, @NASAKennedy on X, or NASA Kennedy on Facebook.

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Jason Costa

NASA’s SpaceX Crew-11 Lands at NASA Kennedy 

NASA’s SpaceX Crew-11 Lands at NASA Kennedy 

Gulfstream jet on runway.
The NASA Gulfstream V carrying NASA astronauts Zena Cardman and Mike Fincke, JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, and Roscosmos cosmonaut Oleg Platonov is seen as it arrives at the Launch and Landing Facility at NASA’s Kennedy Space Center ahead of SpaceX’s Crew-11 mission, Saturday, July 26, 2025, in Florida.
NASA

NASA astronauts Zena Cardman, and Mike Fincke, along with JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui and Roscosmos cosmonaut Oleg Platonov landed shortly after 1:10 p.m. EDT at the Launch and Landing Facility at NASA’s Kennedy Space Center in Florida, following a two-hour flight from Houston. 

Watch Crew-11’s remarks on NASA Kennedy’s social media and YouTube accounts. 

NASA’s SpaceX Crew-11 crew members will spend the remaining few days ahead of their launch to the International Space Station in quarantine and conducting preflight operations at the Neil A. Armstrong Operations and Checkout Building. 

NASA’s SpaceX Crew-11 mission is the company’s 11th crew rotation flight as part of the agency’s Commercial Crew Program. Liftoff is targeted for no earlier than 12:09 p.m. EDT on Thursday, July 31, from Launch Complex 39A at NASA Kennedy aboard a SpaceX Falcon 9 rocket. 

More details about the launch will be posted on the mission blog@NASAKennedy on X, or NASA Kennedy on Facebook.

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Jason Costa

NASA’s SpaceX Crew-11 Departs Houston 

NASA’s SpaceX Crew-11 Departs Houston 

The official portrait of the four members of NASA's SpaceX Crew-11 mission to the International Space Station. From left, are Roscosmos cosmonaut and Mission Specialist Oleg Platonov; NASA astronaut and Pilot Mike Fincke; JAXA (Japan Aerospace Exploration Agency) astronaut and Mission Specialist Kimiya Yui; and NASA astronaut and Commander Zena Cardman.
The official portrait of the four members of NASA’s SpaceX Crew-11 mission to the International Space Station. From left, are Roscosmos cosmonaut and Mission Specialist Oleg Platonov; NASA astronaut and Pilot Mike Fincke; JAXA (Japan Aerospace Exploration Agency) astronaut and Mission Specialist Kimiya Yui; and NASA astronaut and Commander Zena Cardman.
NASA/Robert Markowitz

NASA’s SpaceX Crew-11 crew members are in the air and on their way to the agency’s Kennedy Space Center in Florida to prepare for launch to the International Space Station.  

NASA astronauts Zena Cardman and Mike Fincke, JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, and Roscosmos cosmonaut Oleg Platonov departed from Ellington Field aboard NASA’s Gulfstream near the agency’s Johnson Space Center in Houston at about 11 a.m. EDT and are expected to land around 1 p.m. EDT at NASA Kennedy’s Launch and Landing Facility.  

Upon landing, Crew-11 will be greeted on the runway by representatives from NASA Kennedy and the agency’s Commercial Crew Program, before speaking briefly to members of the media.  After remarks, the crew will head to Astronaut Crew Quarters inside Kennedy’s Neil A. Armstrong Operations and Checkouts Building, where they will continue to quarantine through launch. 

Watch live coverage of the crew arrival media event on NASA Kennedy’s social media and YouTube accounts.  

Liftoff is targeted for no earlier than 12:09 p.m. EDT on Thursday, July 31, from Launch Complex 39A at NASA Kennedy aboard a SpaceX Falcon 9 rocket.  

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Jason Costa

NASA, SpaceX Managers Proceed Toward Crew-11 Launch 

NASA, SpaceX Managers Proceed Toward Crew-11 Launch 

Four astronauts in blue flight suits sit inside a spacecraft, looking toward the camera and smiling.
The four crew members of NASA’s SpaceX Crew-11 mission to the International Space Station train inside a SpaceX Dragon spacecraft in Hawthorne, California. From left to right: Roscosmos cosmonaut Oleg Platonov, NASA astronauts Mike Fincke and Zena Cardman, and JAXA astronaut Kimiya Yui.
SpaceX

After meeting for several hours today, NASA, SpaceX, and international partner teams polled “go” to continue launch preparations following conclusion of the Flight Readiness Review at the agency’s Kennedy Space Center in Florida.  

NASA’s SpaceX Crew-11 remains targeted to launch no earlier than 12:09 p.m. EDT on Thursday, July 31, aboard a SpaceX Falcon 9 rocket at Launch Complex 39A at NASA Kennedy.  

The Flight Readiness Review is an in-depth assessment on the readiness of flight for SpaceX’s transportation system, mission operations, support functions, and readiness of the International Space Station to support the crewed flight to the International Space Station. 

Crew-11 crew members, NASA astronauts Zena Cardman, commander, and Mike Fincke, pilot, along with mission specialists JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui,  and Roscosmos cosmonaut Oleg Platonov are scheduled to depart NASA’s Johnson Space Center in Houston on Saturday, July 26, for the launch site at NASA’s Kennedy Space Center in Florida. The crew will share a few remarks with the public about 1 p.m. after arrival at the Launch and Landing Facility. Watch the arrival event live on Kennedy’s social account. 

NASA, SpaceX, and the international partners leadership, supporting the Crew-11 mission, will hold a prelaunch news conference at 5:30 p.m. on Wednesday, July 30, to discussion mission preparations. 

More details about the launch will be posted on the mission blog@NASAKennedy on X, or NASA Kennedy on Facebook. 

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Jason Costa