Expedition 74 Crew Promotes Innovation with Stem Cell and Space Tech Research

Expedition 74 Crew Promotes Innovation with Stem Cell and Space Tech Research

The official portrait of the Expedition 74 crew on the International Space Station. Top row from left, Commander Mike Fincke and Flight Engineer Zena Cardman, both NASA astronauts, JAXA (Japan Aerospace Exploration Agency) Flight Engineer Kimiya Yui, and Roscosmos Flight Engineer Oleg Platonov. Bottom row, Roscosmos Flight Engineer Sergey Kud-Sverchkov, NASA astronaut Chris Williams, and Roscosmos Flight Engineer Sergei Mikaev.
The official portrait of the Expedition 74 crew on the International Space Station. Top row from left, Commander Mike Fincke and Flight Engineer Zena Cardman, both NASA astronauts, JAXA (Japan Aerospace Exploration Agency) Flight Engineer Kimiya Yui, and Roscosmos Flight Engineer Oleg Platonov. Bottom row, Roscosmos Flight Engineer Sergey Kud-Sverchkov, NASA astronaut Chris Williams, and Roscosmos Flight Engineer Sergei Mikaev.

Stem cells, materials research, and a technology demo topped the research schedule for the Expedition 74 crew on Thursday. The seven International Space Station residents also worked on a host of lab maintenance including Japanese cargo operations and preparations for upcoming rack transfers.

NASA Flight Engineer Zena Cardman kicked off her day inside the Destiny laboratory module peering at stem cells through a microscope for the StemCellEx-IP1 investigation. She was helping investigators demonstrate the successful production of stem cells in space that are superior to those manufactured on Earth. Results may also advance regenerative medicine for damaged organs and tissues. Later she swapped a gas analyzer, that scans the station’s atmosphere for nitrogen, carbon dioxide, and more, inside the Tranquility module.

JAXA (Japan Aerospace Exploration Agency) Flight Engineer Kimiya Yui began his shift installing a materials exposure experiment inside the Kibo laboratory module’s airlock. The research hardware will be placed in the vacuum of space exposing a variety of materials to space radiation, extreme temperature changes, and more to benefit a range of Earth and space industries. Yui then installed an experimental carbon dioxide removal device in Kibo and wrapped it with soundproof insulation to reduce noise during its operation. The advanced hardware is being studied to inform advanced life support systems for Artemis lunar spacecraft.

NASA Flight Engineer Chris Williams, with a little bit of assistance from Cardman and Yui, spent most of his shift loading cargo inside JAXA’s HTV-X1 that is due to leave the station’s Earth-facing port on the Harmony module in late January. He also had time set aside to replace an air filter, turn on a fluorescent microscope, and swap out hardware on a portable computer tablet.

Station Commander Mike Fincke of NASA spent his shift deconfiguring and removing hardware from a science rack that will soon be transferred inside the HTV-X1. Shortly after waking up, Fincke took a test for an experiment documenting how crews sleep while living off the Earth and without the normal day-night cycle, also called circadian rhythm. Afterward, he performed a leak check on a recycle tank inside Tranquility.

Roscosmos cosmonaut Oleg Platonov started his shift measuring his mass attaching himself to a device that applies a known force with the resulting force providing an output using a form of Newton’s Second Law of Motion. Platonov then worked throughout the day on life support maintenance, inspecting cables, and uninstalling hardware that provides functionality to the European robotic arm.

Cosmonauts Sergey Kud-Sverchkov and Sergei Mikaev, who have been aboard the station since Nov. 27 with Williams, worked throughout the day on a variety of life support maintenance tasks. At the end of his shift, Kud-Sverchkov later installed Earth observation hardware programmed to automatically landmarks on the ground during the crew’s sleep shift. Mikaev wiped down surfaces inside the Roscosmos modules to prevent microbial growth.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

NASA JPL Unveils Rover Operations Center for Moon, Mars Missions

NASA JPL Unveils Rover Operations Center for Moon, Mars Missions

5 min read

Preparations for Next Moonwalk Simulations Underway (and Underwater)

This video highlights the Rover Operations Center at NASA’s Jet Propulsion Laboratory. A center of excellence for current and future rover, aerial, and other surface missions, the ROC will support partnerships and technology transfer to catalyze the next generation of Moon and Mars surface missions. Credit: NASA/JPL-Caltech

The center leverages AI along with JPL’s unique infrastructure, unrivaled tools, and years of operations expertise to support industry partners developing future planetary surface missions.  

NASA’s Jet Propulsion Laboratory in Southern California on Wednesday inaugurated its Rover Operations Center (ROC), a center of excellence for current and future surface missions to the Moon and Mars. During the launch event, leaders from the commercial space and AI industries toured the facilities, participated in working sessions with JPL mission teams, and learned more about the first-ever use of generative AI by NASA’s Perseverance Mars rover team to create future routes for the robotic explorer. 

The center was established to integrate and innovate across JPL’s planetary surface missions while simultaneously forging strategic partnerships with industry and academia to advance U.S. interests in the burgeoning space economy. The center builds on JPL’s 30-plus years of experience developing and operating Mars surface missions, including humanity’s only helicopter to fly at Mars as well as the only two active planetary surface missions. 

“The Rover Operations Center is a force multiplier,” said JPL Director Dave Gallagher. “It integrates decades of specialized knowledge with powerful new tools, and exports that knowledge through partnerships to catalyze the next generation of Moon and Mars surface missions. As NASA’s federally funded research and development center, we are chartered to do exactly this type of work — to increase the cadence, the efficiency, and the impact for our transformative NASA missions and to support the commercial space market as they take their own giant leaps.” 

A rover drives down an incline as a group of people watch from a distance.
Rover prototype ERNEST (Exploration Rover for Navigating Extreme Sloped Terrain) demonstrates some of its advanced mobility and autonomy capabilities in JPL’s Mars Yard.
NASA/JPL-Caltech

Genesis of ROC 

Through decades of successful Mars rover missions, JPL has continuously improved the unique autonomy, robotic capabilities, and best practices that have been demanded by increasingly complex robotic explorers. The ROC offers an accessible centralized structure to facilitate future exploration efforts. 

“Our rovers are lasting longer and are more sophisticated than ever before. The scientific stakes are high, as we have just witnessed with the discovery of a potential biosignature in Jezero Crater by the Perseverance mission. We are starting down a decade of unprecedented civil and commercial exploration at the Moon, which will require robotic systems to assist astronauts and support lunar infrastructure,” said Matt Wallace, who heads JPL’s Exploration Systems Office. “Mobile vehicles like rovers, helicopters, and drones are the most dynamic and challenging assets we operate. It’s time to take our game up a notch and bring everybody we can with us.”  

A man, illuminated by white light, talking to a group of people in a room that is otherwise dark and dimly lit with blue light.
Michael Thelen of JPL’s Exploration Systems Office discusses the newly inaugurated Rover Operations Center in JPL’s historic Space Flight Operations Facility on Dec. 10.
NASA/JPL-Caltech

Future forward  

A key focus of the ROC is on the more rapid infusion of higher-level autonomy into surface missions through partnerships with the AI and commercial space industries. The objective is to catalyze change to deliver next-generation science and exploration capabilities for the nation and NASA. 

As NASA’s only federally funded research and development center, JPL has been evolving vehicle autonomy since the 1990s, when JPL began developing Sojourner, the first rover on another planet. Improvements to vehicle independence over the years have included the evolution of autonomy in sampling activities, driving, and science-target selection. Most recently, those improvements have extended to the development of Perseverance’s ability to autonomously schedule and execute many commanded energy-intensive activities, like keeping warm at night, as it sees fit. This capability allows the rover to conserve power, which it can reallocate in real time to perform more science or longer drives. 

With the explosion of AI capabilities, the ROC rover team is leaving no Mars stone unturned in the hunt for future efficiencies.  

“We had a small team complete a ‘three-week challenge,’ applying generative AI to a few of our operational use cases. During this challenge, it became clear there are many opportunities for AI infusion that can supercharge our capabilities,” said Jennifer Trosper, ROC program manager at JPL. “With these new partnerships, together we will infuse AI into operations to path-find the next generation of capabilities for science and exploration.”  

Håvard Grip, chief pilot of NASA’s Mars Ingenuity Helicopter — the only aircraft to fly on another planet — offers insights into aerial exploration of the Red Planet at the lab’s 25-Foot Space Simulator, which subjects spacecraft to the harsh conditions of space.

During the ROC’s inauguration, attendees toured JPL operations facilities, including where the rover drivers plan their next routes. They also visited JPL’s historic Mars Yard, which reproduces Martian terrain to test rover capabilities, and the massive 25-Foot Space Simulator that has tested spacecraft from Voyagers 1 and 2 to Perseverance to America’s next generation of lunar landers. A panel discussion explored the historical value of rovers and aerial systems like the Ingenuity Mars Helicopter in planetary surface exploration. Also discussed was the promise of a new public-private partnership opportunity across a virtual network of operational missions.  

Attendees were briefed on tiered engagement options for partners, from mission architecture support to autonomy integration, testing, and operations. These opportunities extend to science and human precursor robotic missions, as well as to human-robotic interaction and spacewalks for astronauts on the Moon and Mars. 

A highlight for event participants came when the Perseverance team showcased how the ROC’s generative AI can assist rover planners in creating future routes for the rover. The AI analyzed high-resolution orbital images of Jezero Crater and other relevant data and then generated waypoints that kept Perseverance away from hazardous terrain. 

Managed for NASA by Caltech, JPL is the home of the Rover Operations Center (ROC).  

To learn more about the ROC, visit:

https://www.jpl.nasa.gov/roc

News Media Contact

DC Agle
Jet Propulsion Laboratory, Pasadena, Calif.
818-393-9011
agle@jpl.nasa.gov

2025-137

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Dec 10, 2025

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scarney1

Station Trio Back on Earth; Expedition 74 Keeps Up Science, Maintains Systems

Station Trio Back on Earth; Expedition 74 Keeps Up Science, Maintains Systems

NASA astronaut and Expedition 73 Flight Engineer Mike Fincke smiles for a portrait during research operations for the Droplets fluid physics investigation. Fincke was inside the International Space Station's Destiny laboratory module exploring how particles behave inside fluids. The microgravity study may inform commercial in-space manufacturing techniques and improve optical materials and pollution removal operations.
NASA astronaut Mike Fincke smiles for a portrait during research operations for the Droplets fluid physics investigation that explores how particles behave inside fluids. The study may inform commercial in-space manufacturing techniques and improve optical materials and pollution removal operations.
NASA

Expedition 73 has ended and NASA astronaut Jonny Kim has returned to Houston and Roscosmos cosmonauts Sergey Ryzhikov and Alexey Zubritsky have returned to Moscow. The trio is now readapting to Earth’s gravity after living aboard the International Space Station in weightlessness for 245 days.

Expedition 74 is now underway with veteran NASA astronaut Mike Fincke as commander leading six flight engineers including NASA astronauts Zena Cardman and Chris Williams, JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, and Roscosmos cosmonauts Oleg Platonov, Sergey Kud-Sverchkov and Sergei Mikaev.

Fincke spent his Wednesday primarily inside the Tranquility module replacing orbital plumbing components on the waste and hygiene compartment, the station’s restroom. The veteran astronaut also prepared cargo and life support racks for removal and reinstallation throughout the orbital outpost’s U.S. segment. The rack transfer work will continue into next week.

Cardman processed stem cell samples for stowage in a science freezer ahead of their return to Earth next year for a study demonstrating on-orbit pharmaceutical manufacturing and regenerative medicine. She also measured air flow throughout the U.S. modules and printed out an updated spacewalking checklist.

Williams exercised for research while pedaling on the Destiny laboratory module’s exercise cycle. He worked out wearing breathing gear and electrodes measuring his aerobic output and cardiovascular health. Afterward, he powered on a fluorescent research microscope then collected carbon dioxide waste samples from an atmospheric cleaner for analysis.

Yui reviewed the rack removal and replacement steps that he Cardman and Williams will assist Fincke with over the next several days. He then worked inside the Kibo laboratory module servicing an experimental carbon  dioxide removal device.

Flight Engineers Kud-Sverchkov and Mikaev, who have been aboard the station with Williams since Nov. 27, had a light duty day on Wednesday with some time set aside for photographic inspections and Elektron oxygen generator maintenance. Flight Engineer Oleg Platonov began his shift on orbital plumbing tasks in the station’s Roscosmos segment. Next, he assisted Mikaev with the Elektron job then wrapped up his shift installing hardware that enables the European robotic arm to be remotely controlled from Earth.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

25 Years of Space Station Technology Driving Exploration 

25 Years of Space Station Technology Driving Exploration 

NASA and its partners have supported humans continuously living and working in space since November 2000. After 25 years of habitation, the International Space Station continues to be a proving ground for technology that powers NASA’s Artemis campaign, future lunar missions, and human exploration of Mars.  

Take a look at key technology advancements made possible by research aboard the orbiting laboratory.  

Robots at work in orbit  

NASA astronaut and Expedition 72 Commander Suni Williams onboard space station with the Astrobee robotic free-flyer in the Kibo laboratory module.
NASA astronaut Suni Williams checks out the Astrobee robotic free-flyer inside the International Space Station’s Kibo laboratory module during a demonstration of satellite capture techniques. This technology could help extend the life of satellites and reduce space debris.
NASA

Robots have been critical to the space station’s success. From the Canadian-built Canadarm2, which assembled large portions of the orbiting laboratory and continues to support ongoing operations, especially during spacewalks, robotic technology on station has evolved to include free-flying assistants and humanoid robots that have extended crew capabilities and opened new paths for exploration. 

The station’s first robotic helpers arrived in 2003. The SPHERES robots – short for Synchronized Position Hold, Engage, Reorient, Experimental Satellite – served on station for over a decade, supporting environmental monitoring, data collection and transfer, and materials testing in microgravity.  

NASA’s subsequent free-flying robotic system, Astrobee, built on the lessons learned from SPHERES. Known affectionately as Honey, Queen, and Bumble, the three Astrobees work autonomously or via remote control by astronauts, flight controllers, or researchers on the ground. They are designed to complete tasks such as inventory, documenting experiments conducted by astronauts, or moving cargo throughout the station, and they can be outfitted and programmed to carry out experiments. 

NASA and partners have also tested dexterous humanoid robots aboard the space station. Robonaut 1 and its more advanced successor, Robonaut 2, were designed to use the same tools as humans, so they could work safely with crew with the potential to take over routine tasks and high-risk activities.  

Advanced robotic technologies will play a significant role in NASA’s mission to return to the Moon and continue on to Mars and beyond. Robots like Astrobee and Robonaut 2 have the capacity to become caretakers for future spacecraft, complete precursor missions to new destinations, and support crew safety by tackling hazardous tasks. 

Closing the loop: recycling air and water in space 

A woman replaces a tank aboard the space station.
ESA (European Space Agency) astronaut Samantha Cristoforetti works on a Regenerative Environmental Control and Life Support System (ECLSS) recycle tank remove-and-replace task aboard the International Space Station. 
ESA

Living and working in space for more than two decades requires technology that makes the most of limited resources. The space station’s life support systems recycle air and water to keep astronauts healthy and reduce the need for resupply from Earth. 

The station’s Environmental Control and Life Support System (ECLSS) removes carbon dioxide from the air, supplies oxygen for breathing, and recycles wastewater—turning yesterday’s coffee into tomorrow’s coffee. It is built around three key components: the Water Recovery System, Air Revitalization System, and Oxygen Generation System. The water processor reclaims wastewater from crew members’ urine, cabin humidity, and the hydration systems inside spacesuits for spacewalks, converting it into clean, drinkable water. 

A man drinks a cup of coffee aboard the space station.
NASA astronaut Kjell Lindgren celebrates International Coffee Day aboard the orbital laboratory with a hand-brewed cup of coffee in space, brewed using the Capillary Beverage Cup.
NASA

The air revitalization system filters carbon dioxide and trace contaminants from the cabin atmosphere, ensuring the air stays safe to breathe. The oxygen generation system uses electrolysis to split water into hydrogen and oxygen, providing a steady supply of breathable air. Today, these systems can recover around 98% of the water brought to the station, a vital step toward achieving long-duration missions where resupply will not be possible. 

The lessons learned aboard the space station will help keep Artemis crews healthy on the Moon and shape the closed-loop systems needed for future expeditions to Mars. 

Advancing 3D printing technology for deep space exploration 

A space station crew member holds the first metal part that was 3D printed in space.
The first metal part 3D printed in space.
ESA

Additive manufacturing, also known as 3D printing, is regularly used on Earth to quickly produce a variety of devices. Adapting this process for space could let crew members create tools and parts for maintenance and repair as needed and save valuable cargo space. 

Research aboard the orbiting laboratory is helping to develop this capability.  

The space station’s first 3D printer was installed in November 2014. That device produced more than a dozen plastic tools and parts, demonstrating that the process could work in low Earth orbit. Subsequent devices tested different printer designs and functionality, including the production of parts from recycled materials and simulated lunar regolith. In August 2024, a device supplied by ESA produced the first metal 3D-printed product.    

The space station also has hosted studies of a form of 3D printing called biological printing or bioprinting. This process uses living cells, proteins, and nutrients as raw materials to potentially produce human tissues for treating injury and disease. So far, a knee meniscus and live human heart tissue have been printed onboard.

The ability to manufacture things in space is especially important in planning for future missions to the Moon and Mars because additional supplies cannot quickly be sent from Earth and cargo capacity is limited. 

We have the solar power 

An astronaut outside of the International Space Station has one hand on a truss near a solar panel. Her other hand is by her head. Reflected in her helmet is astronaut Nichole Ayers, also in a white spacesuit, taking the photo. Earth's blue water and white clouds can be seen in the background.
NASA astronaut and Expedition 72 flight engineer Anne McClain is pictured near one of the space station’s main solar arrays during a spacewalk to upgrade the orbital outpost’s power generation system and relocate a communications antenna.
NASA/Nichole Ayers

As the space station orbits Earth, its four pairs of solar arrays soak up the sun’s energy to provide electrical power for the numerous research and science investigations conducted every day, as well as the continued operations of the orbiting laboratory. 

In addition to harnessing the Sun’s energy for its operations, the space station has provided a platform for innovative solar power research. At least two dozen investigations have tested advanced solar cell technology – evaluating the cells’ on-orbit performance and monitoring degradation caused by exposure to the extreme environment of space. These investigations have demonstrated technologies that could enable lighter, less expensive, and more efficient solar power that could improve the design of future spacecraft and support sustainable energy generation on Earth.  

One investigation – the Roll-Out Solar Array – has already led to improvements aboard the space station. The successful test of a new type of solar panel that rolls open like a party favor and is more compact than current rigid panel designs informed development of the ISS Roll-Out Solar Arrays (iROSAs). The six iROSAs were installed during a series of spacewalks between 2021 and 2023 and provided a 20% to 30% increase in space station power. 

Connecting students to station science 

A group of people sit around a circular table in a dark room, engaged in a video call displayed on a large screen showing the interior of a space module with an astronaut visible.
The Kibo Robot Programming Challenge students watch in real time as the free-flying robot Astrobee performs maneuvers aboard the space station, executing tasks based on their input to test its capabilities.
NASA/Helen Arase Vargas

For 25 years, the orbital outpost has served as a global learning platform, advancing STEM education and connecting people on Earth to life in space. Every experiment, in-flight downlink, and student-designed payload helps students see science in action and share humanity’s pursuit of discovery. 

The first and longest-running education program on the space station is ISS Ham Radio, known as Amateur Radio on the International Space Station (ARISS), where students can ask questions directly to crew members aboard the space station. Since 2000, ARISS has connected more than 100 astronauts with over 1 million students across 49 U.S. states, 63 countries, and every continent. 

Through Learn with NASA, students and teachers can explore hands-on activities and astronaut-led experiments that demonstrate how physics, biology, and chemistry unfold in microgravity. 

Students worldwide also take part in research inspired by the space station. Programs like Genes in Space and Cubes in Space let learners design experiments for orbit, while coding and robotics competitions such as the Kibo Robot Programming Challenge allows students to program Astrobee free-flying robots aboard the orbiting laboratory. 

As NASA prepares for Artemis missions to the Moon, the space station continues to spark curiosity and inspire the next generation of explorers. 

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Linda E. Grimm