Muscle and Exercise Studies to Maintain Crew Health in Space

Muscle and Exercise Studies to Maintain Crew Health in Space

ASA astronaut and Expedition 73 Flight Engineer Jonny Kim conducts a ham radio session and takes notes inside the International Space Station's Columbus laboratory module.
NASA astronaut Jonny Kim conducts a ham radio session and takes notes inside the International Space Station’s Columbus laboratory module.
NASA

Maintaining muscles and monitoring astronaut health in space were the top research subjects aboard the International Space Station on Wednesday. The Expedition 73 crew also replaced critical life support hardware and serviced a variety of experimental gear.

The lack of gravity weighing down on a human living in space contributes to muscle loss since it takes much less effort to move around in weightlessness. Spaceflight crews exercise daily for two hours to counteract space-caused muscle atrophy and bone loss to stay healthy in microgravity and remain in shape for the eventual return to Earth.

Scientists are studying electrical muscle stimulation in combination with exercising in space to improve muscle function, reduce workout times, and design lighter exercise equipment. NASA Flight Engineers Nichole Ayers and Jonny Kim joined each other in the Columbus laboratory module for the muscle study that may benefit future long-duration space flights as well as patients on Earth with mobility issues. Ayers wore electrodes that sent electrical signals to her legs as Kim operated the biomedical equipment that also recorded how her muscles responded.

Next, Ayers removed the electrodes then wore a sensor-packed headband and vest collecting her heart and breathing rate as she worked out on the advanced resistive exercise device that mimics free weights on Earth and then pedaled on an exercise cycle. Researchers will use the health data to continuously adjust crew exercise plans and improve aerobic and cardiovascular conditioning in microgravity.

Ayers and Kim later assisted NASA Flight Engineer Anne McClain as she replaced a catalytic reactor in the Tranquility module. The catalytic reactor introduces oxygen into the station’s water processor assembly and oxidizes organic material in the wastewater. Station Commander Takuya Onishi from JAXA (Japan Aerospace Exploration Agency) helped the trio conclude the maintenance work as he reinstalled hardware removed in Tranquility so the crew could access the advanced life support components.

Onishi began his day in the Kibo laboratory module troubleshooting and inspecting combustion research hardware in the Multipurpose Small Payload Rack. Onishi then replaced a device, the Microgravity Measurement Apparatus, that measures the vibrations Kibo experiences due to astronaut activities and spacecraft dockings that may affect sensitive science experiments.

Roscosmos cosmonauts Sergey Ryzhikov and Kirill Peskov also participated in an exercise study as they took turns jogging on the Zvezda service module’s treadmill for a fitness evaluation. Doctors will use the data to determine a crew member’s energy requirements to stay fit in space and ensure readiness for strenuous activities such as spacewalks and the return to Earth’s gravity. Roscosmos Flight Engineer Alexey Zubritskiy started his shift cleaning ventilation systems and smoke detectors. He then trained to perform medical procedures on the orbital outpost including eye checks, needle injections, injury treatments, and more.

The Progress 91 cargo craft docked to the rear port of Zvezda fired its engines for nearly 12 minutes on Wednesday. The reboost lifts the space station’s orbit to the correct altitude for the approach and docking of the Progress 93 cargo craft planned for September.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Ax-4 Returns Home; Expedition 73 Studies Space Effects on Heart, Nervous System

Ax-4 Returns Home; Expedition 73 Studies Space Effects on Heart, Nervous System

Expedition 73 Flight Engineer Jonny Kim from NASA and Axiom Mission 4 Commander Peggy Whitson work together inside the International Space Station's Destiny laboratory module setting up research hardware to culture patient-derived cancer cells, model their growth in microgravity, and test a state-of-the-art fluorescence microscope. Results may lead to earlier cancer detection methods, development of advanced cancer treatments, and promote future stem cell research in space.
NASA astronaut Jonny Kim from works with Axiom Mission 4 private astronaut Peggy Whitson inside the International Space Station setting up research hardware on June 28, 2025.
NASA

Axiom Mission 4 (Ax-4) splashed down in the Pacific Ocean at 2:31 a.m. PDT Tuesday ending a 20-day spaceflight that saw the private astronauts perform critical microgravity research aboard the International Space Station. Veteran astronaut Peggy Whitson, who has accumulated 695 days in space over five missions, led Pilot Shubhanshu Shukla and Mission Specialists Sławosz Uznański-Wiśniewski and Tibor Kapu back to Earth aboard the SpaceX Dragon spacecraft.

Back on the orbital outpost, the Expedition 73 crew kicked off several days of human research activities starting with exploring how the human heart and nervous system adapt to weightlessness. NASA Flight Engineers Jonny Kim and Anne McClain joined each other in the Columbus laboratory module on Tuesday for heart scans using the Ultrasound 2 device to understand how living in space affects blood flow. McClain then partnered with NASA Flight Engineer Nichole Ayers and studied how an astronaut’s nervous system, or sense of balance, adjusts to microgravity. McClain wore virtual reality goggles and responded to visual stimuli as Ayers monitored and operated the hardware with assistance from doctors on the ground in real time. Both studies are part of the CIPHER suite of 14 human research experiments.

Kim later assisted station Commander Takuya Onishi of JAXA (Japan Aerospace Exploration Agency) as he worked in the Tranquility module for upcoming electrical and life support maintenance. The duo removed a variety of exercise racks and orbital plumbing components to access electrical hardware for maintenance and begin installing a new catalytic reactor.

Roscosmos cosmonauts Alexey Zubritskiy and Kirill Peskov continued unpacking cargo from inside the Progress 92 resupply ship that delivered about three tons of food, fuel, and supplies to the Expedition 73 crew on July 5. Veteran cosmonaut Sergey Ryzhikov spent his day checking electronics gear and servicing space physics research equipment.

The docked Progress 91 cargo craft will fire its engines on Wednesday for several minutes boosting the station’s orbit to the correct altitude for the arrival of the SpaceX Crew-11 mission. Crew-11 is targeted to launch no earlier than 12:09 p.m. EDT on July 31 aboard the Dragon spacecraft for a docking on Aug. 2 to the Harmony module’s space-facing port. NASA astronaut Zena Cardman will lead Crew-11 with Pilot Mike Fincke of NASA and Mission Specialists Kimiya Yui of JAXA and Oleg Platonov of Roscosmos.

50 years ago today, two different spacecraft from the United States and the Soviet Union launched from opposites of the world to begin an era of international cooperation in space. Two days later, the Apollo spacecraft with NASA astronauts Tom Stafford, Vance Brand, and Deke Slayton docked with the Soyuz spacecraft carrying cosmonauts Alexei Leonov and Valery Kubasov. Stafford and Leonov opened the hatches between both spacecraft, shook hands, and conducted research before undocking two days later. The experience gained from the Apollo-Soyuz mission would inform operations on the International Space Station that will reach 25 years of continuous human habitation on Nov. 2 this year.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Ax-4 Undocks from Station Inside Dragon for Earth Return

Ax-4 Undocks from Station Inside Dragon for Earth Return

The SpaceX Dragon spacecraft with the Axiom Mission 4 crew inside is pictured docked to the International Space Station's space-facing port on the Harmony module.
The SpaceX Dragon spacecraft with the Axiom Mission 4 crew inside is pictured docked to the International Space Station’s space-facing port on the Harmony module. In the foreground, is the Canadarm2 robotic arm and its latching end effector.
NASA+

The SpaceX Dragon spacecraft undocked at 7:15 a.m. EDT from the space-facing port of the International Space Station’s Harmony module, completing the fourth private astronaut mission to the orbiting laboratory, Axiom Mission 4 (Ax-4). 

Dragon is slowly maneuvering away from the station into an orbital track that will return the crew and its cargo safely to Earth, targeting a splashdown off the coast of California on Tuesday, July 15.

NASA’s coverage will end in approximately 30 minutes when space station joint operations with Axiom Space and SpaceX conclude. Axiom Space will resume coverage of Dragon’s re-entry and splashdown on the company’s website

The Dragon spacecraft is returning with more than 580 pounds of cargo, including NASA hardware and data from over 60 experiments conducted during the mission. 

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

NASA+ is Live as Ax-4 Prepares to Undock from Station

NASA+ is Live as Ax-4 Prepares to Undock from Station

The Axiom Mission 4 (Ax-4) and Expedition 73 crews join each other for a group portrait inside the International Space Station's Harmony module. In the front row (from left) are, Ax-4 crewmates Tibor Kapu, Peggy Whitson, Shubhanshu Shukla, and Sławosz Uznański-Wiśniewski with Expedition 73 crewmates Anne McClain and Takuya Onishi. In the rear are, Expedition 73 crewmates Alexey Zubritskiy, Kirill Peskov, Sergey Ryzhikov, Jonny Kim, and Nichole Ayers.
The Axiom Mission 4 (Ax-4) and Expedition 73 crews join each other for a group portrait on June 26, 2025. In the front row (from left) are, Ax-4 crewmates Tibor Kapu, Peggy Whitson, Shubhanshu Shukla, and Sławosz Uznański-Wiśniewski with Expedition 73 crewmates Anne McClain and Takuya Onishi. In the rear are, Expedition 73 crewmates Alexey Zubritskiy, Kirill Peskov, Sergey Ryzhikov, Jonny Kim, and Nichole Ayers.
NASA

NASA’s live coverage is underway on NASA+ for the undocking of the fourth private astronaut mission, Axiom Mission 4 (Ax-4), from the International Space Station. Learn how to watch NASA content through a variety of platforms, including social media.

NASA’s coverage will end approximately 30 minutes after undocking when space station joint operations with Axiom Space and SpaceX conclude. Axiom Space will resume coverage of re-entry and splashdown on the company’s website

At 5:07 a.m. EDT, the crew closed the hatch between the SpaceX Dragon spacecraft and the space station in preparation for undocking and the return of private astronauts Peggy Whitson, Shubhanshu Shukla, Sławosz Uznański-Wiśniewski, and Tibor Kapu.

The Dragon spacecraft is scheduled to undock from the orbiting laboratory at 7:05 a.m., heading for a targeted splashdown on Tuesday, July 15, off the coast of California. The spacecraft is returning more

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Ax-4 Boards Dragon and Closes Hatch for Departure

Ax-4 Boards Dragon and Closes Hatch for Departure

(From left) Ax-4 Mission Specialist Tibor Kapu, Pilot Shubhanshu Shukla, Commander Peggy Whitson, and Mission Specialist Sławosz Uznański-Wiśniewski wave from inside the Space Dragon spacecraft.
(From left) Ax-4 Mission Specialist Tibor Kapu, Pilot Shubhanshu Shukla, Commander Peggy Whitson, and Mission Specialist Sławosz Uznański-Wiśniewski wave from inside the Space Dragon spacecraft.
Axiom Space

At 5:07 a.m. EDT, the hatch closed between the SpaceX Dragon spacecraft and the International Space Station in preparation for the undocking and return to Earth of Axiom Mission 4 (Ax-4), with astronauts Peggy Whitson, Shubhanshu Shukla, Sławosz Uznański-Wiśniewski, and Tibor Kapu.

Live coverage on NASA+ will resume at 6:45 a.m. before the scheduled undocking of the Dragon spacecraft at 7:05 a.m. NASA’s coverage will end approximately 30 minutes after undocking when space station joint operations with Axiom Space and SpaceX conclude.

Undocking begins the private astronaut mission’s journey home with splashdown off the coast of California, targeted for Tuesday, July 15. Axiom Space will resume coverage of Dragon’s re-entry and splashdown on the company’s website.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia