Expedition 74 Crew Promotes Innovation with Stem Cell and Space Tech Research

Expedition 74 Crew Promotes Innovation with Stem Cell and Space Tech Research

The official portrait of the Expedition 74 crew on the International Space Station. Top row from left, Commander Mike Fincke and Flight Engineer Zena Cardman, both NASA astronauts, JAXA (Japan Aerospace Exploration Agency) Flight Engineer Kimiya Yui, and Roscosmos Flight Engineer Oleg Platonov. Bottom row, Roscosmos Flight Engineer Sergey Kud-Sverchkov, NASA astronaut Chris Williams, and Roscosmos Flight Engineer Sergei Mikaev.
The official portrait of the Expedition 74 crew on the International Space Station. Top row from left, Commander Mike Fincke and Flight Engineer Zena Cardman, both NASA astronauts, JAXA (Japan Aerospace Exploration Agency) Flight Engineer Kimiya Yui, and Roscosmos Flight Engineer Oleg Platonov. Bottom row, Roscosmos Flight Engineer Sergey Kud-Sverchkov, NASA astronaut Chris Williams, and Roscosmos Flight Engineer Sergei Mikaev.

Stem cells, materials research, and a technology demo topped the research schedule for the Expedition 74 crew on Thursday. The seven International Space Station residents also worked on a host of lab maintenance including Japanese cargo operations and preparations for upcoming rack transfers.

NASA Flight Engineer Zena Cardman kicked off her day inside the Destiny laboratory module peering at stem cells through a microscope for the StemCellEx-IP1 investigation. She was helping investigators demonstrate the successful production of stem cells in space that are superior to those manufactured on Earth. Results may also advance regenerative medicine for damaged organs and tissues. Later she swapped a gas analyzer, that scans the station’s atmosphere for nitrogen, carbon dioxide, and more, inside the Tranquility module.

JAXA (Japan Aerospace Exploration Agency) Flight Engineer Kimiya Yui began his shift installing a materials exposure experiment inside the Kibo laboratory module’s airlock. The research hardware will be placed in the vacuum of space exposing a variety of materials to space radiation, extreme temperature changes, and more to benefit a range of Earth and space industries. Yui then installed an experimental carbon dioxide removal device in Kibo and wrapped it with soundproof insulation to reduce noise during its operation. The advanced hardware is being studied to inform advanced life support systems for Artemis lunar spacecraft.

NASA Flight Engineer Chris Williams, with a little bit of assistance from Cardman and Yui, spent most of his shift loading cargo inside JAXA’s HTV-X1 that is due to leave the station’s Earth-facing port on the Harmony module in late January. He also had time set aside to replace an air filter, turn on a fluorescent microscope, and swap out hardware on a portable computer tablet.

Station Commander Mike Fincke of NASA spent his shift deconfiguring and removing hardware from a science rack that will soon be transferred inside the HTV-X1. Shortly after waking up, Fincke took a test for an experiment documenting how crews sleep while living off the Earth and without the normal day-night cycle, also called circadian rhythm. Afterward, he performed a leak check on a recycle tank inside Tranquility.

Roscosmos cosmonaut Oleg Platonov started his shift measuring his mass attaching himself to a device that applies a known force with the resulting force providing an output using a form of Newton’s Second Law of Motion. Platonov then worked throughout the day on life support maintenance, inspecting cables, and uninstalling hardware that provides functionality to the European robotic arm.

Cosmonauts Sergey Kud-Sverchkov and Sergei Mikaev, who have been aboard the station since Nov. 27 with Williams, worked throughout the day on a variety of life support maintenance tasks. At the end of his shift, Kud-Sverchkov later installed Earth observation hardware programmed to automatically landmarks on the ground during the crew’s sleep shift. Mikaev wiped down surfaces inside the Roscosmos modules to prevent microbial growth.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Station Trio Back on Earth; Expedition 74 Keeps Up Science, Maintains Systems

Station Trio Back on Earth; Expedition 74 Keeps Up Science, Maintains Systems

NASA astronaut and Expedition 73 Flight Engineer Mike Fincke smiles for a portrait during research operations for the Droplets fluid physics investigation. Fincke was inside the International Space Station's Destiny laboratory module exploring how particles behave inside fluids. The microgravity study may inform commercial in-space manufacturing techniques and improve optical materials and pollution removal operations.
NASA astronaut Mike Fincke smiles for a portrait during research operations for the Droplets fluid physics investigation that explores how particles behave inside fluids. The study may inform commercial in-space manufacturing techniques and improve optical materials and pollution removal operations.
NASA

Expedition 73 has ended and NASA astronaut Jonny Kim has returned to Houston and Roscosmos cosmonauts Sergey Ryzhikov and Alexey Zubritsky have returned to Moscow. The trio is now readapting to Earth’s gravity after living aboard the International Space Station in weightlessness for 245 days.

Expedition 74 is now underway with veteran NASA astronaut Mike Fincke as commander leading six flight engineers including NASA astronauts Zena Cardman and Chris Williams, JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, and Roscosmos cosmonauts Oleg Platonov, Sergey Kud-Sverchkov and Sergei Mikaev.

Fincke spent his Wednesday primarily inside the Tranquility module replacing orbital plumbing components on the waste and hygiene compartment, the station’s restroom. The veteran astronaut also prepared cargo and life support racks for removal and reinstallation throughout the orbital outpost’s U.S. segment. The rack transfer work will continue into next week.

Cardman processed stem cell samples for stowage in a science freezer ahead of their return to Earth next year for a study demonstrating on-orbit pharmaceutical manufacturing and regenerative medicine. She also measured air flow throughout the U.S. modules and printed out an updated spacewalking checklist.

Williams exercised for research while pedaling on the Destiny laboratory module’s exercise cycle. He worked out wearing breathing gear and electrodes measuring his aerobic output and cardiovascular health. Afterward, he powered on a fluorescent research microscope then collected carbon dioxide waste samples from an atmospheric cleaner for analysis.

Yui reviewed the rack removal and replacement steps that he Cardman and Williams will assist Fincke with over the next several days. He then worked inside the Kibo laboratory module servicing an experimental carbon  dioxide removal device.

Flight Engineers Kud-Sverchkov and Mikaev, who have been aboard the station with Williams since Nov. 27, had a light duty day on Wednesday with some time set aside for photographic inspections and Elektron oxygen generator maintenance. Flight Engineer Oleg Platonov began his shift on orbital plumbing tasks in the station’s Roscosmos segment. Next, he assisted Mikaev with the Elektron job then wrapped up his shift installing hardware that enables the European robotic arm to be remotely controlled from Earth.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Soyuz Crew Lands Ending Eight-Month Space Research Journey

Soyuz Crew Lands Ending Eight-Month Space Research Journey

Soyuz MS-27 crew members (frm left) NASA astronaut Jonny Kim and Roscosmos cosmonauts Sergey Ryzhikov and Alexey Zubritsky pose for a portrait at the Gagarin Cosmonaut Training Center in Russia.
Soyuz MS-27 crew members (frm left) NASA astronaut Jonny Kim and Roscosmos cosmonauts Sergey Ryzhikov and Alexey Zubritsky pose for a pre-flight portrait at the Gagarin Cosmonaut Training Center in Russia.
GCTC

At 12:03 a.m. EST (10:03 a.m. local time), the Soyuz MS-27 spacecraft made a parachute-assisted landing on the steppe of Kazakhstan, southeast of the town of Dzhezkazgan.

NASA astronaut Jonny Kim and Roscosmos cosmonauts Sergey Ryzhikov and Alexey Zubritsky orbited Earth 3,920 times and traveled nearly 104 million miles over the course of their 245-day mission. The Soyuz MS-27 spacecraft launched and docked with the space station on April 8.

This was Kim’s first spaceflight, where he served as flight engineer for Expedition 72 and 73. This also was Zubritsky first trip to the space station. Ryzhikov now has logged a total of 603 days in space during three trips to the orbital complex, ranking him 13th all time.

The three crew members will fly by helicopter to Karaganda, Kazakhstan, where recovery teams are based. Kim will board a NASA aircraft and return to Houston, while Ryzhikov and Zubritsky will depart for their training base in Star City, Russia.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Live on NASA+: Three Soyuz Crewmates Landing on Earth Soon

Live on NASA+: Three Soyuz Crewmates Landing on Earth Soon

The Soyuz MS-27 spacecraft approaches the International Space Station 259 miles above Morocco on the African continent. The Soyuz spacecraft would dock shortly afterward to the Prichal module bringing NASA astronaut Jonny Kim and Roscosmos cosmonauts Sergey Ryzhikov and Alexey Zubritsky to the orbital outpost.
The Soyuz MS-27 spacecraft approaches the International Space Station above Morocco on the African continent on April 8, 2025.
NASA

NASA’s live coverage of the Soyuz MS-27 return is underway on NASA+Amazon Prime, and YouTube. Learn how to stream NASA content through a variety of platforms, including social media.

The Soyuz spacecraft, with NASA astronaut Jonny Kim and Roscosmos cosmonauts Sergey Ryzhikov and Alexey Zubritsky aboard, will make a parachute-assisted landing at 12:03 a.m. EST on Tuesday, Dec. 9 (10:03 a.m. local time in Kazakhstan), on the steppe of Kazakhstan, southeast of the city of Dzhezkazgan. The spacecraft will execute its deorbit burn at approximately 11:09 p.m.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Soyuz Undocks from Station, Crew Heads for Earth Return

Soyuz Undocks from Station, Crew Heads for Earth Return

The Soyuz MS-27 crew spacecraft undocks from the Prichal module to return three Expedition 73 crew members to Earth.
The Soyuz MS-27 crew spacecraft undocks from the Prichal module to return three Expedition 73 crew members to Earth.
NASA

At 8:41 p.m. EST, the Soyuz MS-27 spacecraft undocked from the International Space Station’s Prichal module with NASA astronaut Jonny Kim and Roscosmos cosmonauts Sergey Ryzhikov and Alexey Zubritsky aboard.  

NASA’s live coverage of deorbit burn, entry, and landing will begin at 10:30 p.m. on NASA+, Amazon Prime, and YouTube. Learn how to stream NASA content through a variety of platforms, including social media. 

The spacecraft will make a parachute-assisted landing at 12:03 a.m. on Tuesday, Dec. 9 (10:03 a.m. local time in Kazakhstan), on the steppe of Kazakhstan, southeast of the city of Dzhezkazgan. 

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia