Hazardous Material Summary Tables (HMSTs)

Hazardous Material Summary Tables (HMSTs)

3 min read

Preparations for Next Moonwalk Simulations Underway (and Underwater)

space toxicologist
A space toxicologist at NASA JSC.
NASA

Hazardous Materials Summary Tables (HMSTs) are a compilation of the chemical, biological, and flammability hazards of materials on a given flight or mission. HMSTs are required by Safety for all Programs, including but not limited to ISS, Commercial Crew Program (CCP), Multi Purpose Crew Vehicle (MPCV), and Gateway. Johnson Space Center (JSC) toxicologists evaluate the toxic hazard level of all liquids, gases, particles, or gels flown on or to any manned U.S. spacecraft. The biosafety hazard level and flammability levels are assigned by JSC microbiologists and materials experts and are documented in an HMST and in a computerized in-flight version of the HMST called the HazMat (Hazardous Materials) database.

How To Obtain Toxicological Hazard Assessments

“Requirements for Submission of Data Needed for Toxicological Assessment of Chemical and Biologicals to be Flown on Manned Spacecraft”

  • JSC 27472 (PDF, 766KB) defines the terms “chemicals” and “biological materials” as applied to items being flown on or to any U.S. spacecraft. It explains who must submit information to the JSC toxicologists concerning the materials to be flown and specifies what information is needed. It provides schedules, formats, and contact information.
  • Additional US requirements for biological materials can be found on the Biosafety Review Board (BRB) page.
  • Additional US requirements for environmental control and life support (ECLS) assessments can be found in JSC 66869 (PDF, 698KB).

Data Submission

For all flights to ISS and all Artemis requests (Orion, Gateway, Human Lander System (HLS)), please submit data via the electronic hazardous materials summary table (eHMST) tool. If you do not have access to this tool, please submit a NAMS request for access to JSC – CMC External Tools. Please reference eHMST training for more information

NOTE:  For experimental payloads/hardware planned for launch on a Russian vehicle, stowed and/or operated on the Russian Segment of ISS, or planned for return or disposal on a Russian vehicle, we strongly encourage payload providers to submit biological and chemical data to the Russian Institute for Biomedical Problems (moukhamedieva@imbp.ru OR barantseva@imbp.ru).

Hazard Assessments

Toxicological hazard assessments are conducted according to JSC 26895 – Guidelines for Assessing the Toxic Hazard of Spacecraft Chemicals and Test Materials. The resulting Toxicity Hazard Level (THL) in combination with the BioSafety Level (BSL) and Flammability Hazard Level (FHL) form the basis for the combined Hazard Response Level (HRL) used for labeling and operational response per flight rule B20-16.

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Last Updated

Dec 03, 2025

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Robert E. Lewis

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Ahmed El-Rasheedy

Toxicology Analysis of Spacecraft Air

Toxicology Analysis of Spacecraft Air

4 min read

Preparations for Next Moonwalk Simulations Underway (and Underwater)

SpaceX Crew-1 uses a GSC en route to the ISS
SpaceX Crew-1 Pilot Victor Glover and Mission Specialist Shannon Walker work with a Grab Sample Container (GSC) in the SpaceX Crew Dragon Resilience spacecraft while en route to the ISS.
NASA

Toxicology and Environmental Chemistry (TEC) monitors airborne contaminants in both spacecraft air and water. In-flight monitors are employed to provide real-time insight into the environmental conditions on ISS. Archival samples are collected and returned to Earth for full characterization of ISS air and water.

Real-time in-flight air analytical instruments include the Air Quality Monitors (AQM), carbon dioxide (CO2 monitors), and a compound specific analyzer for combustion products (CSA-CP). Real-time in-flight water monitoring capabilities include the colorimetric water quality monitoring kit (CWQMK) and the ISS total organic carbon analyzer (TOCA).

Post-flight analyses are performed on archival samples of spacecraft air and water obtained at specific times and locations during a mission. Air archival samples are collected using “grab sample containers” (GSC) and formaldehyde badges. The U.S. and Russian water recovery systems on the ISS process atmospheric moisture (U.S. and Russian systems) and urine distillate (U.S. system only) into clean, potable water for the crew to use.  The Water Kit is utilized to collect archival samples of the potable water and are routinely returned to the ground to monitor the quality of the water produced by the systems.  Samples of condensate and wastewater are also collected and returned to check for the presence of contaminants that could break through the water recovery systems.   

Results of Post-Flight Analysis of In-Flight Air Samples  (Most Recent First)

    

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Dec 03, 2025

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Robert E. Lewis

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Ahmed El-Rasheedy

NASA Awards Lunar Freezer System Contract

NASA Awards Lunar Freezer System Contract

The letters NASA on a blue circle with red and white detail, all surrounded by a black background
Credit: NASA

NASA has selected the University of Alabama at Birmingham to provide the necessary systems required to return temperature sensitive science payloads to Earth from the Moon.

The Lunar Freezer System contract is an indefinite-delivery/indefinite-quantity award with cost-plus-fixed-fee delivery orders. The contract begins Thursday, Dec. 4, with a 66-month base period along with two optional periods that could extend the award through June 3, 2033. The contract has a total estimated value of $37 million.

Under the contract, the awardee will be responsible for providing safe, reliable, and cost-effective hardware and software systems NASA needs to maintain temperature-critical science materials, including lunar geological samples, human research samples, and biological experimentation samples, as they travel aboard Artemis spacecraft to Earth from the lunar surface. The awarded contractor was selected after a thorough evaluation by NASA engineers of the proposals submitted. NASA’s source selection authority made the selection after reviewing the evaluation material based on the evaluation criteria contained in the request for proposals.

For information about NASA and other agency programs, visit:

https://www.nasa.gov

-end-

Tiernan Doyle
Headquarters, Washington
202-358-1600
tiernan.doyle@nasa.gov  

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Tiernan P. Doyle

NASA’s Fly Foundational Robots Demo to Bolster In-Space Infrastructure

NASA’s Fly Foundational Robots Demo to Bolster In-Space Infrastructure

NASA and industry partners will fly and operate a commercial robotic arm in low Earth orbit through the Fly Foundational Robots mission set to launch in late 2027. This mission aims to revolutionize in-space operations, a critical capability for sustainably living and working on other planets. By enabling this technology demonstration, NASA is fostering the in-space robotics industry to unlock valuable tools for future scientific discovery and exploration missions.   

“Today it’s a robotic arm demonstration, but one day these same technologies could be assembling solar arrays, refueling satellites, constructing lunar habitats, or manufacturing products that benefit life on Earth,” said Bo Naasz, senior technical lead for In-space Servicing, Assembly, and Manufacturing (ISAM) in the Space Technology Mission Directorate at NASA Headquarters in Washington. “This is how we build a dominant space economy and sustained human presence on the Moon and Mars.”

a golden satellite with solar arrays extended, with the limb of Earth in the background
Artist concept of the FFR Mission’s robotic system payload atop the Astro Digital spacecraft. The robotic arm, provided by Motiv Space Systems, will perform robotic demonstrations in orbit.
Motiv Space Systems

The Fly Foundational Robots (FFR) mission will leverage a robotic arm from small business Motiv Space Systems capable of dexterous manipulation, autonomous tool use, and walking across spacecraft structures in zero or partial gravity. This mission could enable ways to repair and refuel spacecraft, construct habitats and infrastructure in space, maintain life support systems on lunar and Martian surfaces, and serve as robotic assistants to astronauts during extended missions. Advancing robotic systems in space could also enhance our understanding of similar technologies on Earth across industries including construction, medicine, and transportation.  

To demonstrate FFR’s commercial robotic arm in space, NASA’s Space Technology Mission Directorate is contracting with Astro Digital to provide a hosted orbital test through the agency’s Flight Opportunities program.  

Guest roboticists will have the opportunity to contribute to the FFR mission, and participation will allow them to use Motiv’s robotic platform as a testbed and perform unique tasks. NASA will serve as the inaugural guest operator and is currently seeking other interested U.S. partners to participate.  

The future of in-space robotics relies on testing robotic operations in space prior to launching more complex and extensive servicing and refueling missions. Through FFR, the demonstration of Motiv’s robotic arm operations in space will begin to push open the door to endless possibilities. 

NASA’s Fly Foundational Robots demonstration is funded through the NASA Space Technology Mission Directorate’s ISAM portfolio and managed by NASA’s Goddard Space Flight Center in Greenbelt, Maryland. Motiv Space Systems of Pasadena, California, will supply the mission’s robotic arm system through a NASA Small Business Innovation Research Phase III award. Astro Digital of Littleton, Colorado, will flight test Motiv’s robotic payload through NASA’s Flight Opportunities program managed by NASA’s Armstrong Flight Research Center in Edwards, California. 

Learn more about In-space Servicing, Assembly, and Manufacturing at NASA.

By Colleen Wouters
NASA’s Goddard Space Flight Center, Greenbelt, Md.

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Rob Garner

Waxing Gibbous Moon

Waxing Gibbous Moon

The Moon is nearly full and a deep gray-brown color in this image. Below it is Earth’s blue atmosphere and and white clouds. This photo was taken from the International Space Station.
NASA

The waxing gibbous moon rises above Earth’s blue atmosphere in this photograph taken from the International Space Station on Oct. 3, 2025, as it orbited 263 miles above a cloudy Atlantic Ocean off the coast of Quebec, Canada.

In our entire solar system, the only object that shines with its own light is the Sun. That light always beams onto Earth and the Moon from the direction of the Sun, illuminating half of our planet in its orbit and reflecting off the surface of the Moon to create moonlight. Sometimes the entire face of the Moon glows brightly. Other times we see only a thin crescent of light. Sometimes the Moon seems to disappear. These shifts are called Moon phases. The waxing gibbous phase comes just before the full moon.

Learn more about our Moon.

Image credit: NASA

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Monika Luabeya