Crew Studies Space Biology Advancing Health in Space and on Earth

Crew Studies Space Biology Advancing Health in Space and on Earth

JAXA (Japan Aerospace Exploration Agency) astronaut and Expedition 73 Commander Takuya Onishi inspects science hardware inside the Kibo laboratory module's Solid Combustion Experiment Module, a space fire safety research facility, aboard the International Space Station.
Astronaut and Expedition 73 Commander Takuya Onishi inspects combustion science hardware inside the Kibo laboratory module.
NASA

Synthetic DNA, how cells respond to weightlessness, and cognitive performance in space wrapped up the week aboard the International Space Station. The Expedition 73 crew is also gearing up for a spacewalk to ready the orbital outpost for a new rollout solar array.

Space biology is helping doctors understand how humans adapt to living in space and providing countermeasures to keep crews healthy on long duration missions farther away from Earth. Results may also provide advanced treatments for ailments on Earth.

A new experiment recently delivered aboard the SpaceX Dragon cargo spacecraft is exploring the ability to manufacture DNA-like nanomaterials that could be used to deliver therapeutics, vaccines, and regenerative medicine. NASA Flight Engineers Anne McClain and Nichole Ayers kicked off that experiment on Friday mixing solutions to create the nanomaterial products inside the Kibo laboratory module’s Life Science Glovebox. Ayers then pointed an electromagnetic light tool at the newly created materials, measured the wavelengths emitted, and evaluated their space-manufactured quality. The samples will be returned to Earth for further analysis.

McClain and Ayers are also getting ready for a spacewalk scheduled for May 1. The duo will exit the Quest airlock into the vacuum of space and spend six-and-a-half hours preparing the station’s port side truss structure for a new rollout solar array and relocating an antenna that communicates with visiting vehicles. McClain spent an hour-and-a-half on Friday studying the paths she and Ayers will take to their worksites outside the space station.

A second investigation unloaded from Dragon and activated by station Commander Takuya Onishi of JAXA (Japan Aerospace Exploration Agency) is observing how cells sense gravity. Onishi spent Friday processing cell samples inside Kibo’s Cell Biology Experiment Facility before placing the samples inside a confocal microscope for observation. How those cells samples adapt to microgravity may help scientists provide advanced treatments for space-caused as well as Earth-based conditions such muscle atrophy, osteoporosis, and aging-like symptoms.

NASA Flight Engineer Jonny Kim focused his research activities on learning how living in space is affecting his cognition, or the ability to think and perform actions in microgravity. CIPHER is a suite of 14 human research studies looking at the physical and mental changes an astronaut experiences during spaceflight. Kim first collected his blood samples for processing and analysis. Next, he took a series of tests that included simulating Canadarm2 robotic arm maneuvers on a computer. The Spatial Cognition portion of the CIPHER study will help doctors learn about and prevent any adverse effects of space on a crew member’s brain structure and function.

Roscosmos Flight Engineer Kirill Peskov wrapped up an Earth observation experiment that imaged the planet’s nighttime atmospheric glow in near-ultraviolet wavelengths. Cosmonauts Sergey Ryzhikov and Alexey Zubritsky spent their day on life support maintenance throughout the orbiting lab’s Roscosmos segment.

Robotics controllers completed the extraction late Thursday of the Atomic Clock Ensemble in Space (ACES) experiment from Dragon’s unpressurized trunk. ACES will be installed outside the Columbus laboratory module for a variety of tests including testing Einstein’s theory of general relativity as well as researching fundamental physics using high accuracy atomic clocks in space.

Learn more about station activities by following the space station blog, @space_station and @ISS_Research on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Searching for the Dark in the Light

Searching for the Dark in the Light

2 min read

Searching for the Dark in the Light

A color close-up photo of the Martian surface shows a pale tan-orange rock, with a more or less circular face showing, that has grooves or lines emanating from a center point like rays.
The Perseverance rover acquired this image of the “Hare Bay” abrasion patch using its SHERLOC WATSON camera (Scanning Habitable Environments with Raman and Luminescence for Organics and Chemicals, and the Wide Angle Topographic Sensor for Operations and eNgineering), located on the turret at the end of the rover’s robotic arm. This image was acquired on April 18, 2025 (Sol 1479, or Martian day 1,479 of the Mars 2020 mission) at the local mean solar time of 12:53:57.
NASA/JPL-Caltech

Written by Eleanor Moreland, Ph.D. Student Collaborator at Rice University 

Perseverance has been busy exploring lower “Witch Hazel Hill,” an outcrop exposed on the edge of the Jezero crater rim. The outcrop is composed of alternating light and dark layers, and naturally, the team has been trying to understand the makeup of and relationships between the light and dark layers. A few weeks ago, we sampled one of the light-toned layers, which we discovered was made up of very small clasts, or fragments of rocks or minerals, at “Main River.” Since then, we have learned that the dark layers tend to be composed of larger clasts compared to the light layers, and we’ve been searching for a place to sample this coarser-grained rock type. Sometimes, these coarser-grained rocks also contain spherules, which are of great interest to the science team because they provide clues about the process that formed these layered rocks.

Perseverance first looked at a dark layer at “Puncheon Rock” with an abrasion. We then examined a dark layer at “Wreck Apple,” near “Sally’s Cove,” but we could not identify a suitable surface to abrade. So, while team members searched for other locations to study the coarse-grained units and spherules, Perseverance drove south to “Port Anson.”

A color photo from the Mars surface shows pale orange, gritty terrain with lighter-colored flat rocks visible above the soil in several areas. At the image center, the Perseverance rover’s mechanical arm, with a boxy instrument at its end, extends from beyond the top of the frame and reaches toward the ground. Its shadow runs along the ground from the center of the frame to the lower left corner of the image. Shadowed portions of the rover are visible along the top of the image frame, and the lower-right corner, while a rover wheel is visible in the lower left.
Perseverance acquired this image of the “Strong Island” workspace near Port Anson using its onboard Front Left Hazard Avoidance Camera A (https://science.nasa.gov/mission/mars-2020-perseverance/rover-components/#eyes). This image was acquired on April 12, 2025 (Sol 1473, or Martian day 1,473 of the Mars 2020 mission) at the local mean solar time of 12:50:32.
NASA/JPL-Caltech

Port Anson was intriguing because, from orbit, it showed a clear contact between the light layers of Witch Hazel Hill and a distinct unit below it. And, although the rocks below the Port Anson contact do show interesting compositional differences with those of Witch Hazel Hill, they weren’t the coarse-grained rocks we were looking for. We still performed an abrasion there, at Strong Island, before driving back up north for another attempt at investigating the coarser-grained rocks.

We aimed for “Pine Pond,” which neighbors “Dennis Pond,” to abrade at “Hare Bay.” With the data just coming down over the weekend, the team will be hard at work to figure out if we captured the coarse grains and spherules, and if it is representative of rocks we have seen before or not. The image below is a close-up of this most recent abrasion patch at Hare Bay — what do you think? Stay tuned to find out! 

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Apr 25, 2025

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NASA Invites Local Middle Schoolers to Explore Agency STEM Careers

NASA Invites Local Middle Schoolers to Explore Agency STEM Careers

A group of grade school students explore the lobby of NASA Glenn's Telecscience Support Center, a facility where researchers operate International Space Station experiments. A NASA expert wearing a white shirt with blue and red stars and jeans clasps her hands and smiles at a student looking up at her. The student is a grade school girl with a light blue shirt and braids with white hair clips. She smiles up at the expert and appears to be asking a question. Other students look on in the background.
Students take a tour of the Glenn International Space Station Payload Operations Center at NASA’s Glenn Research Center in Cleveland, where researchers operate International Space Station experiments, during 4-H Day on June 14, 2024.
Credit: NASA/Jef Janis

Ohio middle school students will step into the shoes of real-world NASA professionals for a day of career exploration and hands-on activities at NASA’s Glenn Research Center in Cleveland. Nearly 200 students are slated to participate in TECH Day at NASA Glenn on May 1, from 10 a.m. to 1 p.m. Media are invited to attend.

TECH Day is designed to inspire and inform the next generation of innovators by introducing them to clear and attainable career pathways into the aerospace industry. Students will tour NASA Glenn facilities, participate in an interactive engineering challenge, and engage with professionals to learn about the wide range of careers in STEM fields.

Student tours will include the following Glenn facilities:

  • Graphics and Visualization Lab, where researchers create engaging projects using virtual and augmented reality
  • Glenn International Space Station Payload Operations Center, where researchers remotely operate experiments aboard the International Space Station
  • Simulated Lunar Operations Laboratory, a unique indoor space designed to mimic the surface of the Moon and Mars
  • 10×10 Supersonic Wind Tunnel, NASA Glenn’s largest and fastest wind tunnel facility

Creating Clear Pathways

Developing early and accessible entry points into STEM careers is essential to meeting the growing demand for a skilled technical workforce. NASA STEM engagement events help students visualize their future and better understand the technical experience needed for a career in the aerospace sector. Opportunities like this equip students with the skills to further technological advancement and become the STEM professionals of tomorrow.

Media interested in attending should contact Jacqueline Minerd at jacqueline.minerd@nasa.gov no later than 5 p.m. Wednesday, April 30. Interviews with experts will take place from 9 to 10 a.m.

For more information on NASA Glenn, visit: 

https://www.nasa.gov/glenn

-end- 

Jacqueline Minerd
Glenn Research Center, Cleveland 
216-433- 6036  
jacqueline.minerd@nasa.gov

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Kelly M. Matter

Sols 4520-4521: Prinzregententorte

Sols 4520-4521: Prinzregententorte

3 min read

Sols 4520-4521: Prinzregententorte

Black-and-white image from a Mars rover showing layered rock formations on a slope, with the rover's shadow in the foreground, and portions of the rover, shadowed but visible, in the four corners of the frame, with a sunlit wheel seen in the lower right.
NASA’s Mars rover Curiosity acquired this image of its target area — including the layered rocks “Hale Telescope” and “Fan Palm” — using its Front Hazard Avoidance Camera on April 22, 2025 (Sol 4518, or Martian day 4,518 of the Mars Science Laboratory mission) at 11:03:37 UTC.
NASA/JPL-Caltech

Written by Scott VanBommel, Planetary Scientist at Washington University

Earth planning date: Wednesday, April 23, 2025

I will start this blog with an apology, an apology because I suspect, by the end of this post, you, the reader, may have a craving for chocolate, or cake, or both. While we saw hints of it in the previous workspace, as captured by Susanne’s blog, today’s workspace featured prominent laminations throughout Curiosity’s sightlines, which presented the science team with the challenge of finding a safe place to utilize APXS (and MAHLI). Perhaps it was because of Easter last weekend, perhaps I needed an early lunch — whatever the cause, I could not shake the visual parallels between the rocks in our workspace, as captured in this blog’s image, and a many-layered-cake such as a Prinzregententorte.

The rover planners rose to the technical challenge, as they always do, and were ultimately able to find a safe area to place APXS on the top of the rock that is prominent just above and left of the center of today’s image. Combined with a green-light from SRAP, Curiosity now had its (cakey) target and could APXS it too. 

Tosol’s APXS and MAHLI target, “Hale Telescope,” is named after the famous landmark located north-northwest of San Diego, California. I, for one, was not familiar with the history of this landmark, including how groundbreaking it was at the time of its development and commissioning through the 1920s, ‘30s, and ‘40s.

Curiosity’s plan tosol started with APXS and MAHLI of Hale Telescope. These activities were complemented by Mastcam images of “Puerto Suelo” and “Potrero Seco,” as well as long-distance imaging by ChemCam of “Torote Bowl,” nearly 1 kilometer (about 0.6 miles) away. Curiosity also imaged and conducted compositional analyses of the layered target “Fan Palm,” slightly offset from Hale Telescope, with LIBS. Our intrepid rover then completed a drive of about 23 meters (about 75 feet) in preparation for the three-sol weekend plan. 

On the second sol of the current plan, Curiosity acquired Navcam images and a suprahorizon movie. The highlight of the second sol, however, arguably was an upgraded version of the AEGIS (Autonomous Exploration for Gathering Increased Science) activity where the rover will autonomously determine its own target to analyze with ChemCam while awaiting further instructions from Earth. The software upgrade will allow Curiosity’s team to know what target the rover chose to observe in time for us to make the weekend plan, even though the observation itself won’t happen on Mars until later.

Mars continues to offer stories written in stone, and like all good stories, the richness lies in the voices layered within. Or chocolate. The data aren’t down yet.

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Apr 25, 2025

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Navigation Technology

Navigation Technology

4 Min Read

Navigation Technology

Maurer stands in the middle of this circular fisheye image, facing the camera, wearing a green t-shirt and black pants. In his right hand, he holds a cube-shaped Astrobee, which has black sides and a white panel facing the camera with two bright blue lights that look sort of like eyes. Maurer is pointing at the Astrobee with his left hand.

ESA astronaut Matthias Maurer sets up an Astrobee for the ReSWARM experiment.

Credits:
NASA

Science in Space April 2025

Humans have always been explorers, venturing by land and sea into unknown and uncharted places on Earth and, more recently, in space. Early adventurers often navigated by the Sun and stars, creating maps that made it easier for others to follow. Today, travelers on Earth have sophisticated technology to guide them.

Navigation in space, including for missions to explore the Moon and Mars, remains more of a challenge. Research on the International Space Station is helping NASA scientists improve navigation tools and processes for crewed spacecraft and remotely controlled or autonomous robots to help people boldly venture farther into space, successfully explore there, and safely return home.

Ayers is wearing a long-sleeved blue shirt and a black headband, facing the camera with her hair floating around her head. In her right hand she holds a small black microphone, which is connected by a thick grey cord to a gold and black box slightly larger than a laptop on the wall of the space station.
NASA astronaut Nichole Ayers talks to students on the ground using ham radio equipment.
NASA

A current investigation, NAVCOM, uses the space station’s ISS Ham Radio program hardware to test software for a system that could shape future lunar navigation. The technology processes signals in the same way as global navigation satellite systems such as GPS, but while those rely on constellations of satellites, the NAVCOM radio equipment receives position and time information from ground stations and reference clocks.

The old made new

Gerst is wearing a black t-shirt and a silver watch on his left wrist. With his right hand, he is holding up to his right eye a black sextant, which has a rectangular eyepiece connected to a curved base with an arm at each end that forms a triangle. He is using is left hand to adjust a knob on the base. Three of the station’s cupola windows are visible behind him.
ESA astronaut Alexander Gerst operates the Sextant Navigation device.
NASA

Sextant Navigation tested star-sighting from space using a hand-held sextant. These mechanical devices measure the angle between two objects, typically the Sun or other stars at night and the horizon. Sextants guided navigators on Earth for centuries and NASA’s Gemini and Apollo missions demonstrated that they were useful in space as well, meaning they could provide emergency backup navigation for lunar missions. Researchers report that with minimal training and practice, crew members of different skill levels produced quality sightings through a station window and measurements improved with more use. The investigation identified several techniques for improving sightings, including refocusing between readings and adjusting the sight to the center of the window.

Navigating by neutron stars

The station’s NICER instrument studies the nature and behavior of neutron stars, the densest objects in the universe. Some neutron stars, known as pulsars, emit beams of light that appear to pulse, sweeping across the sky as the stars rotate. Some of them pulse at rates as accurate as atomic clocks. As part of the NICER investigation, the Station Explorer for X-ray Timing and Navigation Technology or SEXTANT tested technology for using pulsars in GPS-like systems to navigate anywhere in the solar system. SEXTANT successfully completed a first in-space demonstration of this technology in 2017. In 2018, researchers reported that real-time, autonomous X-ray pulsar navigation is clearly feasible and they plan further experiments to fine tune and modify the technology.

Robot navigation

Crews on future space exploration missions need efficient and safe ways to handle cargo and to move and assemble structures on the surface of the Moon or Mars. Robots are promising tools for these functions but must be able to navigate their surroundings, whether autonomously or via remote control, often in proximity with other robots and within the confines of a spacecraft. Several investigations have focused on improving navigation by robotic helpers.

Barratt, wearing a blue t-shirt and khaki pants, is floating horizontally holding on to a blue bar with his right hand and looking up at one of three spherical robots floating in front of him. The spheres are, from left to right, blue, orange, and red. Wakata, wearing a grey t-shirt and green pants, is holding onto a blue bar with both hands and looking to his left.
NASA astronaut Michael Barratt (left) and JAXA astronaut Koichi Wakata perform a check of the SPHERES robots.
NASA

The SPHERES investigation tested autonomous rendezvous and docking maneuvers with three spherical free-flying robots on the station. Researchers reported development of an approach to control how the robots navigate around obstacles and along a designated path, which could support their use in the future for satellite servicing, vehicle assembly, and spacecraft formation flying.

McArthur, wearing a pink t-shirt and khaki pants, is smiling at the camera. In front of her float three cube-shaped robots that have, from left to right, blue, green, and yellow panels.
NASA astronaut Megan McArthur with the three Astrobee robots.
NASA

The station later gained three cube-shaped robots known as Astrobees. The ReSWARM experiments used them to test coordination of multiple robots with each other, cargo, and their environment. Results provide a base set of planning and control tools for robotic navigation in close proximity and outline important considerations for the design of future autonomous free-flyers.

Researchers also used the Astrobees to show that models to predict the robots’ behavior could make it possible to maneuver one or two of them for carrying cargo. This finding suggests that robots can navigate around each other to perform tasks without a human present, which would increase their usefulness on future missions.

Cristoforetti, wearing a grey sweatshirt and a headset, is visible on the left side of this image. She is looking at a laptop and typing on it with her left hand and, with her right, holding a white control stick attached to a large, circular white device on the wall.
ESA astronaut Samantha Cristoforetti working on the Surface Avatar experiment.
ESA

An investigation from ESA (European Space Agency), Surface Avatar evaluated orbit-to-ground remote control of multiple robots. Crew members successfully navigated a four-legged robot, Bert, through a simulated Mars environment. Robots with legs rather than wheels could explore uneven lunar and planetary surfaces that are inaccessible to wheeled rovers. The German Aerospace Center is developing Bert.

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Christian M. Getteau