Vision, Immune System Studies and Hardware Inspections Keep Crew Busy

Vision, Immune System Studies and Hardware Inspections Keep Crew Busy

(From left) Expedition 73 Flight Engineers Anne McClain and Nichole Ayers, both NASA astronauts, take a break and pose for a portrait aboard the International Space Station Destiny laboratory module.
(From left) Expedition 73 Flight Engineers Anne McClain and Nichole Ayers, both NASA astronauts, take a break and pose for a portrait aboard the International Space Station’s Destiny laboratory module.
NASA

Life science was back on the schedule for Wednesday as the Expedition 73 crew studied how living in space affects eye structure and cellular immunity. The International Space Station residents also maintained the upkeep of exercise gear, life support components, and orbital plumbing hardware.

The ongoing space biology investigations aboard the orbital lab constantly informs doctors how astronauts adapt to months of living and working in weightlessness. Scientists extrapolate the continuous research data and are using the insights to protect future crews on longer spaceflight missions to the Moon, Mars, and beyond.

Doctors are exploring potential space-caused changes to crew eye structure and function since vision is critical whether piloting a spacecraft, conducting advanced space science, or performing other mission critical tasks. NASA Flight Engineers Jonny Kim and Nichole Ayers kicked off their shift with a test measuring the electrical responses of the retina to light stimuli. Kim attached electrodes to his forehead and around his eyes and Ayers operated the specialized, data-collecting hardware to understand how the eye adjusts to long-term weightlessness. The study is just one part of the CIPHER suite of 14 human research investigations to learn how to keep crews healthy in space.

Kim later collected and stowed his urine samples in a science freezer for later analysis then swapped a pair of research incubators in the Columbus laboratory module. Ayers moved on to the Tranquility module and replaced orbital plumbing gear that removes inorganic impurities from the station’s water.

Station Commander Takuya Onishi of JAXA (Japan Aerospace Exploration Agency) continued studying how the stress of spaceflight affects cellular immunity helping doctors defend crews against infections. Onishi started his day his processing his blood samples that were incubating for 24 hours inside the Kubik research incubator. Next, he stowed the samples in a science freezer to later analyze the blood cells for signs of space-caused cellular stress or tissue damage. Onishi finally inspected and cleaned an experimental carbon dioxide removal device that also recovers water for oxygen generation.

NASA Flight Engineer Anne McClain spent her day inside Tranquility servicing and inspecting the COLBERT treadmill. The regularly scheduled maintenance activities take place every six months as McClain greased axles, cleaned components, and measured the acoustic volume of the workout device while operating with a crew member. McClain wrapped up her shift in the Quest airlock preparing spacesuit hardware for stowage.

Earth observations were back on the schedule as Roscosmos Flight Engineer Alexey Zubritskiy pointed a camera out a station window and photographed islands in the Pacific Ocean and other landmarks across the Pacific coasts of Asia and North America. Veteran cosmonaut Sergey Ryzhikov deactivated imaging hardware that observes Earth’s nighttime atmosphere in ultraviolet wavelengths. Flight Engineer Kirill Peskov wrapped up several days of training, checkouts, and inspections on the European robotic arm (ERA) attached to the Nauka science module. The ERA can be used to maneuver spacewalkers, payloads, and external hardware on the orbital outpost’s Roscosmos segment.

Learn more about station activities by following the space station blog, @space_station and @ISS_Research on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

Crew Works Space Health and Robotics for Station Upkeep

Crew Works Space Health and Robotics for Station Upkeep

The International Space Station soars into an orbital sunset 259 miles above a cloudy Pacific Ocean northwest of the Hawaiian island chain. At left, the Soyuz MS-26 crew ship is pictured docked to the Rassvet module. At center, the Prichal docking module and the European robotic arm are pictured attached to the Nauka science module.
The European robotic arm (top center) is pictured attached to the Nauka science module as the International Space Station soared into an orbital sunset above a cloudy Pacific Ocean. At left, the Soyuz MS-26 crew ship is pictured docked to the Rassvet module on Nov. 23, 2024.
NASA

Biomedical research topped the science schedule aboard the International Space Station on Tuesday helping doctors understand how weightlessness affects the cardiovascular and immune systems. The Expedition 73 crew members also continued their Earth observation studies, robotic inspection duties, and advanced life support maintenance.

Humans continue to learn how to survive in space after a millennia evolving in Earth’s gravity. Doctors are studying every aspect of an astronaut’s physiology before, during, and after a spaceflight. Data is constantly collected from the numerous human research studies aboard the orbiting lab and added to the ever-growing knowledge base of space biology insights. This gives doctors a clearer picture into how the human body adapts to microgravity helping them design exercise programs, nutritious diets, advanced therapies, and more to keep astronauts healthy on long term space missions.

Astronauts Jonny Kim of NASA and Takuya Onishi of JAXA (Japan Aerospace Exploration Agency), station flight engineer and commander respectively, contributed to the ongoing space biology studies looking at cardiac function and cellular immunity. Kim worked in the Columbus laboratory module as ground surgeons remotely scanned his chest using the ECHO tele-operated ultrasound system. The medical operators were looking for potential space-caused changes in Kim’s heart and artery function for the CIPHER suite of 14 human research investigations. Onishi collected and processed his blood and saliva samples in the Harmony module for the Immunity Assay study. Afterward, he stowed his saliva samples in a science freezer then installed his blood specimens in the Kubik incubator for later analysis. The experiment is observing how spaceflight factors such as weightlessness and radiation affect cellular immune function.

Kim and Onishi later teamed up with NASA Flight Engineer Nichole Ayers and assisted her as she replaced components on an experimental carbon dioxide removal device. Also called the Thermal Amine Scrubber, the advanced life support mechanism is testing a new method that removes carbon dioxide from the station’s atmosphere and recovers water for oxygen generation.

NASA Flight Engineer Anne McClain’s first half of her shift was packed with science supporting physics and robotics research. She first swapped sample cartridges inside the Materials Science Laboratory, a furnace used for discovering new applications for existing materials and new or improved materials. Next, she installed imaging hardware on an Astrobee robotic free-flyer so ground controllers could monitor its autonomous docking maneuvers inside the Kibo laboratory module. McClain then spent the rest of her day on maintenance setting up a wearable radiation monitor, filling water tanks, and finally swapping out a computer hard drive.

Roscosmos Flight Engineer Sergey Ryzhikov, a veteran of two previous space station missions, installed photographic hardware for a pair of Earth observations studies, one looking at the effects of natural and man-made disasters and the other imaging Earth’s nighttime atmosphere in ultraviolet wavelengths. Ryzhikov also joined Flight Engineer Alexey Zubritskiy searching for extra stowage space in the Zvezda and Rassvet modules. Zubritsky later transferred water from the Progress 90 cargo craft docked to the Poisk module into station orbital tanks. Flight Engineer Kirill Peskov activated the European robotic arm (ERA) and monitored its operations using a computer interface and visually inspected the Rassvet module’s docking port.

The SpaceX Dragon cargo spacecraft completed its mission on May 25 after splashing down off the coast of California completing a month-long stay docked to the Harmony module’s space-facing port. Dragon parachuted to Earth returning several tons of completed science experiments, time-critical research samples, and lab hardware for analysis back on Earth.

Learn more about station activities by following the space station blog, @space_station and @ISS_Research on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

SpaceX Dragon Splashes Down off the Coast of California

SpaceX Dragon Splashes Down off the Coast of California

The SpaceX Dragon cargo craft, with its nosecone open, approaches the International Space Station for an automated docking to the Harmony module's space-facing port. Dragon delivered about 6,700 pounds of new science experiments and crew supplies replenishing the Expedition 73 crew.
The SpaceX Dragon cargo craft, with its nosecone open, approaches the International Space Station for an automated docking to the Harmony module’s space-facing port. Dragon delivering about 6,700 pounds of new science experiments and crew supplies on April 22, 2025.
NASA

At 1:44 a.m. EDT, the unpiloted SpaceX Dragon spacecraft splashed down off the coast of California, marking the return of the company’s 32nd commercial resupply services mission to the International Space Station for NASA.

The spacecraft carried back to Earth about 6,700 pounds of supplies and scientific experiments designed to take advantage of the space station’s microgravity environment after undocking at 12:05 p.m., May 23, from the zenith port of the space station’s Harmony module. 

Some of the scientific hardware and samples Dragon will return to Earth include MISSE-20 (Multipurpose International Space Station Experiment), which exposed various materials to space, including radiation shielding and detection materials, solar sails and reflective coatings, ceramic composites for reentry spacecraft studies, and resins for potential use in heat shields. Samples were retrieved on the exterior of the station and can improve knowledge of how these materials respond to ultraviolet radiation, atomic oxygen, charged particles, thermal cycling, and other factors. 

Additionally, Astrobee-REACCH (Responsive Engaging Arms for Captive Care and Handling) is returning to Earth after successfully demonstrating grasping and relocating capabilities on the space station. The REACCH demonstration used Astrobee robots to capture space objects of different geometries or surface materials using tentacle-like arms and adhesive pads. Testing a way to safely capture and relocate debris and other objects in orbit could help address end-of-life satellite servicing, orbit change maneuvers, and orbital debris removal. These capabilities maximize satellite lifespan and protect satellites and spacecraft in low Earth orbit that provide services to people on Earth. 

Books from the Story Time from Space project also will return. Crew members aboard the space station read five science, technology, engineering, and mathematics-related children’s books in orbit and videotaped themselves completing science experiments. Video and data collected during the readings and demonstrations were downlinked to Earth and were posted in a video library with accompanying educational materials.  

Hardware and data from a one-year technology demonstration called OPTICA (Onboard Programmable Technology for Image Compression and Analysis) also will return to Earth. The OPTICA technology was designed to advance transmission of real-time, ultra-high-resolution hyperspectral imagery from space to Earth, and it provided valuable insights for data compression and processing that could reduce the bandwidth required for communication, lowering the cost of acquiring data from space-based imaging systems without reducing the volume of data. This technology also could improve services, such as disaster response, that rely on Earth observations. 

The spacecraft arrived at the orbiting laboratory on April 22 after launching on April 21 on a Falcon 9 rocket from Launch Complex 39A at NASA’s Kennedy Space Center in Florida. 

For more than 24 years, people have lived and worked continuously aboard the International Space Station, advancing scientific knowledge, and conducting critical research for the benefit of humanity and our home planet. Space station research supports the future of human spaceflight as NASA looks toward deep space missions to the Moon under the Artemis campaign and in preparation for future human missions to Mars, as well as expanding commercial opportunities in low Earth orbit and beyond. 

Learn more about station activities by following the space station blog, @space_station and @ISS_Research on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia

SpaceX Dragon Undocks from Station for Splashdown on Sunday

SpaceX Dragon Undocks from Station for Splashdown on Sunday

May 23, 2025: International Space Station Configuration. Four spaceships are parked at the space station including the SpaceX Dragon crew spacecraft, the Soyuz MS-27 crew ship, and the Progress 90 and 91 resupply ships.
May 23, 2025: International Space Station Configuration. Four spaceships are parked at the space station including the SpaceX Dragon crew spacecraft, the Soyuz MS-27 crew ship, and the Progress 90 and 91 resupply ships.
NASA

At 12:05 p.m. EDT, the unpiloted SpaceX Dragon spacecraft undocked from the zenith, or space-facing, port of the International Space Station’s Harmony module following a command from ground controllers at SpaceX. 

After re-entering Earth’s atmosphere, the spacecraft will splash down at approximately 1:45 a.m. on Sunday, May 25, off the coast of California. NASA will post updates on the agency’s space station blog but will not stream the splashdown. 

Filled with about 6,700 pounds of crew supplies, science investigations, and equipment, the spacecraft arrived to the orbiting laboratory on April 22 after it launched April 21 on a Falcon 9 rocket from Launch Complex 39A at NASA’s Kennedy Space Center in Florida for the agency’s SpaceX 32nd commercial resupply services mission. 

Learn more about station activities by following the space station blog, @space_station and @ISS_Research on X, as well as the ISS Facebook and ISS Instagram accounts.

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NASA+ Coverage is Live as SpaceX Dragon Prepares to Undock

NASA+ Coverage is Live as SpaceX Dragon Prepares to Undock

The SpaceX Dragon cargo craft, with its nosecone open, approaches the International Space Station for an automated docking to the Harmony module's space-facing port. Dragon delivered about 6,700 pounds of new science experiments and crew supplies replenishing the Expedition 73 crew.
The SpaceX Dragon cargo craft, with its nosecone open, approaches the International Space Station for an automated docking to the Harmony module’s space-facing port on April 22, 2025.
NASA

NASA’s live coverage of undocking and departure of the agency’s SpaceX 32nd commercial resupply services mission is underway on NASA+. Learn how to watch NASA content through a variety of platforms. 

The unpiloted SpaceX Dragon spacecraft will undock at 12:05 p.m. EDT from the zenith, or space-facing, port of the International Space Station’s Harmony module and fire its thrusters to move a safe distance away from orbiting complex.  After re-entering Earth’s atmosphere, the spacecraft will splash down at approximately 1:45 a.m. on Sunday, May 25, off the coast of California. NASA will post updates on the agency’s space station blog but will not stream the splashdown. 

Filled with about 6,700 pounds of crew supplies, science investigations, and equipment, the spacecraft arrived at the orbiting laboratory on April 22. The spacecraft launched on April 21 on a Falcon 9 rocket from Launch Complex 39A at NASA’s Kennedy Space Center in Florida. 

Learn more about station activities by following the space station blog, @space_station and @ISS_Research on X, as well as the ISS Facebook and ISS Instagram accounts.

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Mark A. Garcia