Friday’s Station Research Looks at Skin Cells, Plant Genetics and Exercise

Friday’s Station Research Looks at Skin Cells, Plant Genetics and Exercise

Astronaut Mark Vande Hei harvests plants and collects samples to analyze later for a space agriculture study.
Astronaut Mark Vande Hei harvests plants and collects samples to analyze later for a space agriculture study.

Friday’s research schedule aboard the International Space Station included exploring how microgravity affects skin cells and cotton genetics. The Expedition 66 crew is also learning how to exercise more effectively in weightlessness.

Living in space has been shown to accelerate the rate of skin aging and a new study delivered aboard the Cygnus space freighter seeks to understand why and protect astronaut’s health. NASA astronaut Tom Marshburn started the experiment on Tuesday and has been servicing skin tissue samples that will grow inside the Life Science Glovebox. The samples will be stowed later in a science freezer and analyzed back on Earth to evaluate the cellular and molecular changes that take place in microgravity.

Weightlessness also affects how plants grow and Flight Engineers Kayla Barron of NASA and Matthias Maurer of ESA (European Space Agency) spent Friday morning exploring genetic expression in cotton cultures. The duo worked on cotton cell samples being grown in the Plant Habitat to learn more about the process of plant regeneration possibly improving crop production on Earth.

Exercise is very important in space as the microgravity environment can lead to muscle and bone loss. Two exercise studies on the orbiting lab are investigating different ways to maximize the effectiveness of working out in microgravity. Maurer began his day pedaling on an exercise cycle wearing the EasyMotion body suit that stimulates muscles. The specialized suit may improve and lessen the duration of exercise sessions in space. Roscosmos Flight Engineer Pyotr Dubrov attached sensors to himself and worked out on the Zvezda service module’s treadmill for a Russian exercise study. That investigation looks at how an exercising crew member expends energy and other physiological factors to help keep crews fit and healthy on a long duration spaceflight.

NASA Flight Engineer Raja Chari worked throughout Friday troubleshooting components on the COLBERT treadmill located in the Tranquility module. NASA astronaut Mark Vande Hei performed orbital plumbing duties and took photos for the ongoing SQuARE archaeological project.

At the end of the day, all six flight engineers joined Commander Anton Shkaplerov and practiced an emergency drill. The seven-member crew located station safety gear, translated along escape paths, and coordinated communications with mission controllers for unlikely events such as an ammonia leak, depressurization, or a fire.


Learn more about station activities by following the space station blog, @space_station and @ISS_Research on Twitter, as well as the ISS Facebook and ISS Instagram accounts.

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Heidi Lavelle

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Station Gears Up for Spacewalks While Conducting Cancer Research

Station Gears Up for Spacewalks While Conducting Cancer Research

This image shows immunofluorescence of breast cancer cells treated with a MicroQuin therapeutic. Staining shows a normal nucleus (blue) and the therapeutic (green) localized to the cell’s endoplasmic reticulum (red). The drug forces the cytoskeleton (yellow) to collapse, inducing cell death. Credits: Scott Robinson, MicroQuin.
This image shows immunofluorescence of breast cancer cells treated with a MicroQuin therapeutic. Staining shows a normal nucleus (blue) and the therapeutic (green) localized to the cell’s endoplasmic reticulum (red). The drug forces the cytoskeleton (yellow) to collapse, inducing cell death. Credits: Scott Robinson, MicroQuin.

Spacewalk preparations and cancer research were among the activities scheduled aboard the International Space Station on Thursday. The Expedition 66 crew also unpacked a U.S. cargo craft and explored using virtual reality while exercising.

NASA astronauts Raja Chari and Kayla Barron began readying the U.S. Quest airlock and collecting tools ahead of a pair of spacewalks planned for mid-March. The duo also reviewed step-by-step spacewalk procedures on a computer using 3D graphics. NASA is continuing to set up the space station’s truss structure for a third set of roll out solar arrays augmenting the orbiting lab’s power system.

Chari earlier partnered with ESA (European Space Agency) Flight Engineer Matthias Maurer investigating how living in space affects visual function. NASA Flight Engineer Thomas Marshburn assisted the duo with the research in the morning before spending the afternoon troubleshooting components on the COLBERT treadmill. Maurer ended his day wearing virtual reality goggles while pedaling on an exercise cycle to learn how to improve the work out experience in space.

A new cancer study started this week after arriving aboard the Cygnus space freighter on Monday. NASA Flight Engineer Mark Vande Hei set up the Life Science Glovebox on Wednesday and began observing tumor cells shipped inside a Cygnus science freezer. On Thursday, Vande Hei continued servicing those samples to better understand the onset and progression of cancer and potentially improve treatments on Earth.

Commander Anton Shkaplerov of Roscosmos was back on plasma physics research Thursday and also transferred cargo from Russia’s ISS Progress 80 cargo craft. Flight Engineer Pyotr Dubrov inspected Russian station modules before exploring ways to maximize space exercise. The duo rounded out the day with eye scans using the Ultrasound 2 device with remote guidance from doctors on the ground.


Learn more about station activities by following the space station blog, @space_station and @ISS_Research on Twitter, as well as the ISS Facebook and ISS Instagram accounts.

Get weekly video highlights at: http://jscfeatures.jsc.nasa.gov/videoupdate/

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Heidi Lavelle

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Crew Kicks Off Skin Aging, Cancer Research and Unloads New Cargo Craft

Crew Kicks Off Skin Aging, Cancer Research and Unloads New Cargo Craft

The Cygnus space freighter is pictured moments away from being captured with the Canadarm2 robotic arm above northern Iraq on Feb. 21, 2022.
The Cygnus space freighter is pictured moments away from being captured with the Canadarm2 robotic arm above northern Iraq on Feb. 21, 2022.

New human research is underway aboard the International Space Station using the microgravity environment to gain unique insights into aging skin cells and cancer tumors. The Expedition 66 crew also continues to unpack cargo from a U.S. cargo craft while keeping up with eye checks to ensure the crew stays healthy in space.

Weightlessness provides scientists a unique opportunity to observe phenomena not possible in Earth’s gravity. Biology including microbes, plants, and humans, changes in response to microgravity and observations are helping NASA plan longer missions farther into space. Doctors on Earth also use the information to improve numerous treatments and conditions on the ground.

Two new biology experiments delivered on Monday aboard the Cygnus space freighter are already being activated on the orbital lab. NASA Flight Engineer Thomas Marshburn set up the Microgravity Science Glovebox and began exploring the cellular and molecular alterations taking place in samples of skin cells. NASA Flight Engineer Mark Vande Hei is observing tumor cells in the Life Science Glovebox to better understand the onset and progression of cancer. Both investigations have the potential to inform space research techniques and improve therapies on Earth.

Astronauts Raja Chari of NASA and Matthias Maurer of ESA (European Space Agency) worked throughout Wednesday continuing to offload the 8,300 pounds of cargo delivered Monday inside Cygnus. NASA Flight Engineer Kayla Barron Barron deactivated space botany hardware then photographed cotton cell samples being harvested for the Plant Habitat-05 space agriculture study.

Working in the orbiting lab’s Russian segment, Commander Anton Shkaplerov studied plasma physics while Flight Engineer Pyotr Dubrov recorded his heart activity wearing a portable electrocardiogram. The duo from Roscosmos then wrapped up the day with more eye and retina checks using medical imaging gear.

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Mark Garcia

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Crew Unloads Cygnus and Begins New Research

Crew Unloads Cygnus and Begins New Research

Astronauts Kayla Barron and Raja Chari harvest cotton cell samples to explore the genetic architecture of plant regeneration in microgravity.
Astronauts Kayla Barron and Raja Chari harvest cotton cell samples to explore the genetic architecture of plant regeneration in microgravity.

A U.S. cargo craft is being unpacked today following its robotic capture and installation at the International Space Station early Monday morning. The Expedition 66 crew also spent Tuesday activating new research and conducting eye checks.

Three NASA astronauts, Mark Vande Hei, Thomas Marshburn, and Kayla Barron, along with ESA (European Space Agency) astronaut Matthias Maurer spent Monday unpacking research samples stowed in science freezers aboard the U.S. Cygnus space freighter. The quartet then loaded the frozen samples into research racks throughout the space station. Some of the new science samples delivered on Monday include skin cells and cancer cells being studied in the microgravity environment to improve human health on Earth and in space.

Marshburn set up the Microgravity Science Glovebox during the afternoon to begin looking at the skin cell samples. The new study getting underway today explores ways to diminish space-caused accelerated skin aging with benefits for astronauts and Earthlings.

Cygnus had launched from Virginia on Saturday as 12:40 p.m. EST loaded with 8,300 pounds of new science experiments, crew supplies, and station hardware. It arrived Monday morning when NASA Flight Engineer Raja Chari, backed up by Barron, commanded the Canadarm2 robotic arm to capture Cygnus at 4:44 a.m. Robotics controllers took over shortly afterward and guided Cygnus to the Unity module where it was installed just over two hours later.

Following a day’s worth of Cygnus cargo transfers on Tuesday, Vande Hei and Chari also participated in eye scans using standard medical imaging gear in the Harmony module. Commander Anton Shkaplerov and Flight Engineer Pyotr Dubrov kicked off the exams in the afternoon helping doctors understand how living in space affects the human eye and retina.

Shkaplerov first spent the morning on an exercise study exploring ways to maximize the effectiveness of working out in weightlessness. Dubrov worked on communications gear and ventilation hardware throughout the station’s Russian segment.

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Mark Garcia

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Cygnus Installed to Station for Cargo Transfers

Cygnus Installed to Station for Cargo Transfers

Feb. 21, 2022: International Space Station Configuration. Five spaceships are parked at the space station including the SpaceX Crew Dragon; Northrop Grumman's Cygnus space freighter; and Russia's Soyuz MS-19 crew ship and the Progress 79 and 80 resupply ships.
Feb. 21, 2022: International Space Station Configuration. Five spaceships are parked at the space station including the SpaceX Crew Dragon; Northrop Grumman’s Cygnus space freighter; and Russia’s Soyuz MS-19 crew ship and the Progress 79 and 80 resupply ships.

Northrop Grumman’s Cygnus spacecraft installation on the International Space Station is now complete. Cygnus launched atop an Antares rocket at 12:40 p.m. EST Saturday, Feb. 19 from NASA’s Wallops Flight Facility in Virginia. At about 4:44 a.m., NASA astronaut Raja Chari, along with NASA astronaut Kayla Barron as backup, captured Cygnus, carrying 8,300 pounds of research, hardware, and science experiments to the International Space Station.

Highlights of space station research facilitated by this mission include:

  • study that examines the effects of a drug on breast and prostate cancer cells
  • a new combustion facility
  • an investigation from Colgate-Palmolive that will leverage the acceleration of skin aging in microgravity to help create and validate an engineered tissue model to serve as a platform for testing potential products to protect aging skin
  • a demonstration of a lithium-ion secondary battery capable of safe, stable operation under extreme temperatures and in a vacuum environment
  • new hydrogen sensors that will be tested for the space station’s oxygen generation system
  • a system that will test hydroponic and aeroponic techniques for plant growth and will allow scientists to observe root growth through video and still images

Findings from these and other investigations aboard the space station will contribute to keeping astronauts healthy during long-duration space travel and demonstrate technologies for future human and robotic exploration missions as part of NASA’s Moon and Mars efforts, including lunar missions through the agency’s Artemis program.

Cygnus will also deliver critical hardware to be installed during the upcoming ISS Roll-Out Solar Array (IROSA) spacewalks, as well as other components for the successful functioning of astronaut life on the space station, such as a trash deployer and acoustic covers for the waste management system.

This Cygnus mission is the first to feature enhanced capabilities that will allow the spacecraft to perform a reboost, using its engines to adjust the space station’s orbit as a standard service for NASA. The agency has one reboost is planned while Cygnus is connected to the orbiting laboratory. A test of the maneuver was performed in 2018 during Cygnus’ ninth resupply mission.

Cygnus will remain at the space station until May before it deploys CubeSats, then disposes of several thousand pounds of trash during its re-entry into Earth’s atmosphere, which will result in its destruction.


Learn more about station activities by following the space station blog@space_station and @ISS_Research on Twitter, as well as the ISS Facebook and ISS Instagram accounts.

Get weekly video highlights at: http://jscfeatures.jsc.nasa.gov/videoupdate/

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Mark Garcia

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