![\"Different](\"https:\/\/www.nasa.gov\/wp-content\/uploads\/2024\/05\/parasitic-wasp-differences.jpg\")
<\/a><\/figure>Blade Shape:<\/strong> The kona<\/em>\u00a0mutant has an angular wing shape in contrast to wild-type\u2019s rounded wing blade (vertical arrows in D\u2013F).<\/div>\n
Background<\/strong>: Like humans, fruit flies (a model organism for spaceflight research) also exhibit immune system dysfunction in space. Despite decades of studies on fruit flies and wasps, little was known about how their immune systems interact with natural parasites in space.\u00a0Drosophila<\/em>\u00a0parasitoid\u00a0wasps modify blood cell function to suppress host immunity. In this spaceflight study (the Fruit Fly-03 Lab flown to the ISS on SpaceX-14<\/a>), naive and parasitized ground and space flies from a tumor-free control and a blood tumor-bearing mutant strain were examined.<\/p>\n Main Findings: <\/strong>Surprisingly, the flies without tumors were more sensitive to space than the flies with tumors. Spaceflight increased immune gene activity and made tumors grow more in the flies. The wasps remained harmful in space, but some developed inheritable physical changes. These changes included \u201caurum\u201d (altered wing color and veins) and \u201ckona\u201d (altered wing shape). Female wasps with two copies of the \u201ckona\u201d mutation could not lay eggs because of defective egg-laying organs.<\/p>\n Impact: <\/strong>This study will Improve our knowledge of how parasites and hosts interact. The results show that we need to study more types of organisms, including plants and their natural parasites, in space. This will help us learn more about how hosts defend themselves and how dangerous parasites can be in space, which is important for astronaut health. Gene expression data from fruit flies (OSD-588<\/a>) and two types of wasps (OSD-609<\/a> & OSD-610<\/a>) are publicly available on NASA\u2019s Open Science Data Repository. This data is available for anyone to use and compare with other spaceflight studies.<\/p>\n Reference:<\/strong> Chou, J., Ramroop, J.,\u00a0 Saravia-Butler, A., Wey, B., Lera, M., Torres, M., Heavner, M., Iyer, J., Mhatre, S,. Bhattacharya, S., Govind, S. Drosophila<\/em> parasitoids go to space: Unexpected effects of spaceflight on hosts and their parasitoids. iScience<\/em>, Volume 27, Issue 1, 2024, 108759, ISSN 2589-0042, https:\/\/doi.org\/10.1016\/j.isci.2023.108759<\/a><\/p>\n Powered by WPeMatico<\/a><\/small><\/p>\n Get The Details…<\/a> How does spaceflight affect tumor-bearing fruit fly hosts and their parasites? Background: Like humans, fruit flies (a model organism for spaceflight research) also exhibit immune system dysfunction in space. Despite decades of studies on fruit flies and wasps, little was known about how their immune systems interact with natural parasites in space.\u00a0Drosophila\u00a0parasitoid\u00a0wasps modify blood cell [\u2026] Continue reading <\/a><\/figure>
Homozygous\u00a0kona<\/em>\u00a0females with defective ovipositors (used for egg laying) how areas of compromised integrity or have branched ends (arrows) compared to the continuous ovipositors with sharp ends from wild-type control wasps.<\/div>\n
\nElizabeth E. Keller <\/p>\n","protected":false},"excerpt":{"rendered":"